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Ion channels as drug targets: the next GPCRs.

作者信息

Kaczorowski Gregory J, McManus Owen B, Priest Birgit T, Garcia Maria L

机构信息

Department of Ion Channels, Merck Research Laboratories, Rahway, NJ 07065, USA.

出版信息

J Gen Physiol. 2008 May;131(5):399-405. doi: 10.1085/jgp.200709946. Epub 2008 Apr 14.

DOI:10.1085/jgp.200709946
PMID:18411331
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2346569/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8300/2346569/15f5422a60be/jgp1310399f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8300/2346569/f01f14c64fa4/jgp1310399f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8300/2346569/15f5422a60be/jgp1310399f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8300/2346569/f01f14c64fa4/jgp1310399f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8300/2346569/15f5422a60be/jgp1310399f02.jpg

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Trends Neurosci. 2007 Nov;30(11):555-63. doi: 10.1016/j.tins.2007.08.004. Epub 2007 Oct 22.
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Automated electrophysiology in drug discovery.药物研发中的自动化电生理学
Elife. 2024 Oct 28;13:RP98534. doi: 10.7554/eLife.98534.
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Front Mol Neurosci. 2024 May 31;17:1414816. doi: 10.3389/fnmol.2024.1414816. eCollection 2024.
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Ion channel inhibition by targeted recruitment of NEDD4-2 with divalent nanobodies.通过二价纳米抗体靶向募集NEDD4-2抑制离子通道
bioRxiv. 2024 May 31:2024.05.28.596281. doi: 10.1101/2024.05.28.596281.
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A synthetic method to assay polycystin channel biophysics.一种用于检测多囊蛋白通道生物物理学的合成方法。
bioRxiv. 2024 Aug 10:2024.05.06.592666. doi: 10.1101/2024.05.06.592666.
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Front Mol Neurosci. 2024 Jan 11;16:1334370. doi: 10.3389/fnmol.2023.1334370. eCollection 2023.
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Membranes (Basel). 2022 Dec 30;13(1):48. doi: 10.3390/membranes13010048.
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