在通用固相载体上高效合成3'-巯基烷基化寡脱氧核糖核苷酸。 - Suppr | 超能文献

An efficient synthesis of 3'-mercaptoalkylated oligodeoxyribonucleotides on the universal solid support.

作者信息

Guzaev A P

机构信息

Institute of Immunology, Lyubuchany, Moscow, USSR.

出版信息

Nucleic Acids Symp Ser. 1991(24):236.

Abstract

摘要

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An efficient synthesis of 3'-mercaptoalkylated oligodeoxyribonucleotides on the universal solid support.在通用固相载体上高效合成3'-巯基烷基化寡脱氧核糖核苷酸。

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Incorporation of point modifications into oligonucleotides during automatic synthesis.

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A facile synthesis of DNA oligomers with modified backbones via the phosphoramidite method without nucleoside base protection.一种通过亚磷酰胺法在无核苷碱基保护的情况下简便合成具有修饰主链的DNA寡聚物的方法。

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Synthesis and application of novel nucleoside phosphonates and phosphoramidites modified at the base moiety.碱基部分修饰的新型核苷膦酸酯和亚磷酰胺的合成与应用。

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Base modification and cloning efficiency of oligodeoxyribonucleotides synthesized by the phosphoramidite method: methyl versus cyanoethyl phosphorus protection.亚磷酰胺法合成的寡脱氧核糖核苷酸的碱基修饰与克隆效率：甲基与氰乙基磷保护

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Rapid synthesis of oligodeoxyribonucleotides. V. Further studies in solid phase synthesis of oligodeoxyribonucleotides through phosphotriester intermediates.寡聚脱氧核糖核苷酸的快速合成。V. 通过磷酸三酯中间体进行寡聚脱氧核糖核苷酸固相合成的进一步研究。

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Solid-phase synthesis of stereoregulated oligodeoxyribonucleoside phosphorothioates.立体规整寡脱氧核糖核苷硫代磷酸酯的固相合成

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Inhibitory properties of double-helix-forming circular oligonucleotides.形成双螺旋的环状寡核苷酸的抑制特性。

Nucleic Acids Res. 1997 Dec 15;25(24):4954-61. doi: 10.1093/nar/25.24.4954.

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Looped oligonucleotides form stable hybrid complexes with a single-stranded DNA.环状寡核苷酸与单链DNA形成稳定的杂交复合物。

Nucleic Acids Res. 1995 Apr 11;23(7):1170-6. doi: 10.1093/nar/23.7.1170.