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头颈部癌症患者的姑息治疗:“我希望能迅速回归正常生活方式”。

Palliative care for patients with head and neck cancer: "I would like a quick return to a normal lifestyle".

作者信息

Goldstein Nathan E, Genden Eric, Morrison R Sean

机构信息

Hertzberg Palliative Care Institute of the Brookdale Department of Geriatrics and Adult Development, Mount Sinai School of Medicine, New York 10029, USA.

出版信息

JAMA. 2008 Apr 16;299(15):1818-25. doi: 10.1001/jama.299.15.1818.

Abstract

Head and neck cancers constitute a diverse group of diseases including malignancies of the oral cavity, oropharynx, larynx, sinuses, and skull base. Treatment of these cancers includes a combination of surgical resection, chemotherapy, and radiation. Due to both the patterns of disease recurrence and the adverse effects of treatments, patients with head and neck cancer often have a complex and prolonged course of illness that is marked by periods of freedom from disease and symptoms interspersed with bouts of serious illness, debility, and numerous physical and psychological symptoms including pain, dysphagia, weight loss, disfigurement, depression, and xerostomia. Thus, management of this disease is best provided by an interdisciplinary team that includes individuals from the disciplines of otolaryngology, palliative care, radiation oncology, oncology, nutrition, speech, and physical and occupational therapy. Using the case of Mr K, we describe the symptoms encountered by patients with head and neck cancer and suggest options for management. We discuss the psychological aspects that affect these patients, including issues such as changes in body image, quality of life, anxiety, and guilt. Finally, we discuss the importance of the interdisciplinary team in the care of these patients and outline the roles of each team member. By providing comprehensive care to patients with malignancies of the head and neck, clinicians can increase the likelihood that patients and their families will be able to obtain the best possible outcomes and quality of life.

摘要

头颈癌是一组多样的疾病,包括口腔、口咽、喉、鼻窦和颅底的恶性肿瘤。这些癌症的治疗包括手术切除、化疗和放疗的联合应用。由于疾病复发模式以及治疗的不良反应,头颈癌患者的病程往往复杂且漫长,其特点是疾病和症状缓解期与严重疾病、虚弱期以及包括疼痛、吞咽困难、体重减轻、毁容、抑郁和口干等众多身心症状交替出现。因此,这种疾病的管理最好由一个跨学科团队来提供,该团队包括来自耳鼻喉科、姑息治疗、放射肿瘤学、肿瘤学、营养、言语以及物理和职业治疗等学科的人员。以K先生的病例为例,我们描述了头颈癌患者所遇到的症状,并提出了管理方案。我们讨论了影响这些患者的心理因素,包括身体形象变化、生活质量、焦虑和内疚等问题。最后,我们讨论了跨学科团队在这些患者护理中的重要性,并概述了每个团队成员的角色。通过为头颈恶性肿瘤患者提供全面护理,临床医生可以提高患者及其家属获得最佳可能结果和生活质量的可能性。

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