Department of Family Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Kaohsiung J Med Sci. 2013 Aug;29(8):444-50. doi: 10.1016/j.kjms.2012.12.005. Epub 2013 Apr 6.
While symptomatic differences exist between younger and older advanced cancer patients, few studies have examined the differences in their care with respect to age. Our goals were to examine the influences of age differences on physical, psychosocial and spiritual distress among advanced cancer patients. Advanced cancer patients who resided in Kaohsiung Medical University Hospital during 2007-2008 were recruited. Data were collected through professional consultants. The influences of age variations on physical, psychosocial and spiritual distress in nonelderly (<60 years old) and elderly (≧60 years old) patients were analyzed. A total of 1013 advanced cancer patients were included in the analyses with 467 nonelderly patients and 546 elderly patients. Nonelderly patients were identified to have a higher baseline pain level (4.0 vs. 2.8, p<0.001), breakthrough pain (19.3% vs. 9.9%, p<0.01), insomnia (6.4% vs. 2.7%, p=0.006), emotional distress (69.0% vs. 60.6%, p=0.013), and unwillingness to pass away because of concern for loved ones (18.8% vs. 11.9%, p=0.003) with significant difference. Elderly ones were concerned about unfulfilled wishes (29.7% vs. 18.4%, p<0.001) in spiritual concerns. After adjustments in regression models, nonelderly age (<60 years old) still revealed significant positive or negative impact on all categories of distress. Patients aged under 60 years have more physical, psychosocial and spiritual suffering. This study suggested that professional practitioners should provide intensive care for vulnerable terminally ill cancer patients.
虽然年轻和老年晚期癌症患者之间存在症状差异,但很少有研究关注年龄对他们的治疗差异。我们的目标是研究年龄差异对晚期癌症患者身体、心理社会和精神困扰的影响。我们招募了 2007-2008 年期间居住在高雄医学大学附属医院的晚期癌症患者。数据通过专业顾问收集。分析了年龄变化对非老年(<60 岁)和老年(≧60 岁)患者身体、心理社会和精神困扰的影响。共有 1013 名晚期癌症患者被纳入分析,其中 467 名非老年患者和 546 名老年患者。非老年患者的基线疼痛水平较高(4.0 比 2.8,p<0.001)、爆发性疼痛(19.3%比 9.9%,p<0.01)、失眠(6.4%比 2.7%,p=0.006)、情绪困扰(69.0%比 60.6%,p=0.013)和因担心亲人而不愿离世(18.8%比 11.9%,p=0.003)的发生率更高,差异有统计学意义。老年患者则在精神关怀方面更关注未完成的愿望(29.7%比 18.4%,p<0.001)。在回归模型调整后,非老年年龄(<60 岁)仍然对所有类别的困扰产生显著的正向或负向影响。年龄在 60 岁以下的患者有更多的身体、心理社会和精神痛苦。本研究表明,专业从业者应给予脆弱的终末期癌症患者强化护理。