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免疫功能正常患者发生原发性鼻疽诺卡菌脑脓肿并继发脑膜炎和脑室炎,采用莫西沙星治疗成功。

Primary Nocardia farcinica brain abscess with secondary meningitis and ventriculitis in an immunocompetent patient, successfully treated with moxifloxacin.

作者信息

Kandasamy J, Iqbal H J, Cooke R P D, Eldridge P R

机构信息

Department of Clinical Neurosurgery, The Walton Centre for Neurology and Neurosurgery NHS Trust, Liverpool, UK.

出版信息

Acta Neurochir (Wien). 2008 May;150(5):505-6. doi: 10.1007/s00701-008-1578-x. Epub 2008 Apr 15.

Abstract

We report a rare case of Nocardia farcinica occipital brain abscess in an immunocompetent patient with no underlying risk factors successfully treated with the antibiotic moxifloxacin. The patient underwent craniotomy and abscess drainage. Initial post-operative treatment with co-trimoxazole produced a limited response. Despite the development of skull base meningitis and ventriculitis subsequent addition of moxifloxacin produced an excellent outcome.

摘要

我们报告了一例罕见的诺卡菌性枕叶脑脓肿病例,患者免疫功能正常,无潜在危险因素,使用抗生素莫西沙星成功治愈。患者接受了开颅手术和脓肿引流。术后初始使用复方新诺明治疗效果有限。尽管出现了颅底脑膜炎和脑室炎,但随后加用莫西沙星取得了极佳的治疗效果。

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