Fellows G A, Kalsi P S, Martin A J
Atkinson Morley Wing, St George's Hospital, London, UK.
Br J Neurosurg. 2007 Jun;21(3):301-3. doi: 10.1080/02688690701365770.
Brain abscess has an incidence of 1 per 100,000 in developed countries and a mortality rate of 10%. Cerebral infections with Nocardia farcinica have a mortality of up to 90%. Nocardial species are important pathogens in immunocompromised hosts, but infections in immunocompetent patients are extremely rare. We report a case of primary brain abscess with N. farcinica in a patient without immunosuppression, which was treated with surgery and a one-year course of oral moxifloxacin.
在发达国家，脑脓肿的发病率为十万分之一，死亡率为10%。鼻疽诺卡菌引起的脑部感染死亡率高达90%。诺卡菌属是免疫功能低下宿主中的重要病原体，但在免疫功能正常的患者中感染极为罕见。我们报告一例无免疫抑制患者发生的原发性鼻疽诺卡菌脑脓肿病例，该患者接受了手术治疗及为期一年的口服莫西沙星治疗。
