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与腹腔干狭窄相关的破裂性胰十二指肠动脉瘤的血管内治疗

Endovascular management of ruptured pancreaticoduodenal artery aneurysms associated with celiac axis stenosis.

作者信息

Suzuki Kojiro, Tachi Yasushi, Ito Shinji, Maruyama Kunihiro, Mori Yoshine, Komada Tomohiro, Matsushima Masaya, Ota Toyohiro, Naganawa Shinji

机构信息

Department of Radiology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Shouwa-ku, Nagoya 466-8550, Japan.

出版信息

Cardiovasc Intervent Radiol. 2008 Nov-Dec;31(6):1082-7. doi: 10.1007/s00270-008-9343-3. Epub 2008 Apr 15.

Abstract

The purpose of this study was to assess the efficacy of transcatheter arterial embolization for ruptured pancreaticoduodenal artery (PDA) aneurysms associated with celiac axis stenosis (CS). Seven patients (four men and three women; mean age, 64; range, 43-84) were treated with transcatheter arterial embolization between 2002 and 2007. They were analyzed with regard to the clinical presentation, radiological finding, procedure, and outcome. All patients presented with sudden epigastric pain or abdominal discomfort. Contrast-enhanced CT showed a small aneurysm and retroperitoneal hematoma around the pancreatic head in all patients. The aneurysms ranged from 0.3 to 0.9 cm in size. In one patient, two aneurysms were detected. The aneurysms were located in the pancreaticoduodenal artery (n = 5) and the dorsal pancreatic artery (n = 3). Embolization was performed with microcoils in all aneurysms (n = 8). N-Butyl 2-cyanoacrylate (n = 1) and gelatine particle (n = 1) were also used. Complete occlusion was achieved in four patients. In the other three patients, a significantly reduced flow to the aneurysm remained at final angiography. However, these aneurysms were thrombosed on follow-up CT within 2 weeks. And there was no recurrence of the symptoms and bleeding during follow-up (mean, 28 months; range, 5-65 months) in all patients. In conclusion, transcatheter arterial embolization for PDA aneurysms associated with CS is effective. Significant reduction of the flow to the aneurysm at final angiography may be predictive of future thrombosis.

摘要

本研究的目的是评估经导管动脉栓塞术治疗与腹腔干狭窄(CS)相关的破裂胰十二指肠动脉(PDA)动脉瘤的疗效。2002年至2007年间,7例患者(4例男性,3例女性;平均年龄64岁;范围43 - 84岁)接受了经导管动脉栓塞术治疗。对他们的临床表现、影像学检查结果、手术过程及预后进行了分析。所有患者均表现为突发上腹部疼痛或腹部不适。增强CT显示所有患者胰头周围有小动脉瘤及腹膜后血肿。动脉瘤大小在0.3至0.9厘米之间。1例患者检测到两个动脉瘤。动脉瘤位于胰十二指肠动脉(n = 5)和胰背动脉(n = 3)。所有动脉瘤(n = 8)均采用微弹簧圈进行栓塞。还使用了N - 丁基2 - 氰基丙烯酸酯(n = 1)和明胶颗粒(n = 1)。4例患者实现了完全闭塞。另外3例患者在最终血管造影时动脉瘤血流仍显著减少。然而,这些动脉瘤在随访CT检查中于2周内形成血栓。所有患者在随访期间(平均28个月;范围5 - 65个月)均未出现症状复发及出血情况。总之,经导管动脉栓塞术治疗与CS相关的PDA动脉瘤是有效的。最终血管造影时动脉瘤血流显著减少可能预示着未来会形成血栓。

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