Numata Masahiko, Aoyagi Yoshie, Matsuo Mayumi, Ishikawa Keiichiro, Hanari Nobuyasu, Otsuka Satoko, Tsuda Yoko, Yarita Takashi
Organic Standards Section 2, National Metrology Institute of Japan, 1-1-1, Umezono, Tsukuba, Ibaraki,, 305-8563, Japan.
Anal Bioanal Chem. 2008 Jul;391(6):1985-95. doi: 10.1007/s00216-008-2010-3. Epub 2008 Apr 16.
Four mineral oil certified reference materials (CRMs), NMIJ CRM 7902-a, CRM 7903-a, CRM 7904-a, and CRM 7905-a, have been issued by the National Metrology Institute of Japan, which is part of the National Institute of Advanced Industrial Science and Technology (NMIJ/AIST), for the determination of polychlorinated biphenyls (PCBs). The raw materials for the CRMs were an insulation oil (CRM 7902-a and CRM 7903-a) and a fuel oil (CRM7904-a and CRM 7905-a). A solution of PCB3, PCB8, and technical PCB products, comprising four types of Kaneclor, was added to the oil matrices. The total PCB concentrations in the PCB-fortified oils (CRM 7902-a and CRM 7904-a) are approximately 6 mg kg(-1). In addition, the mineral oils which were not fortified with PCBs were also distributed as CRMs (CRM 7903-a and CRM 7905-a). Characterization of these CRMs was conducted by the NMIJ/AIST, where the mineral oils and the PCB solution were analyzed using multiple analytical methods such as dimethylsulfoxide extraction, normal-phase liquid chromatography, gel permeation chromatography, reversed-phase liquid chromatography, and chromatography using sulfoxide-bonded silica; and/or various capillary columns for gas chromatography, and two ionization modes for mass spectrometry. The target compounds in the mineral oils and those in the PCB solution were determined by one of the primary methods of measurement, isotope dilution-mass spectrometry (ID-MS). Certified values have been provided for 11 PCB congeners (PCB3, 8, 28, 52, 101, 118, 138, 153, 180, 194, and 206) in the CRMs. These CRMs have information values for PCB homologue concentrations determined by using a Japanese official method for determination of PCBs in wastes and densities determined with an oscillational density meter. Because oil samples having arbitrary PCB concentrations between respective property values of the PCB-fortified and nonfortified CRMs can be prepared by gravimetric mixing of the CRM pairs, these CRMs can be used for validation of PCB analyses using various instruments which have different sensitivities.
日本国家计量院（National Metrology Institute of Japan，隶属于日本国立先进工业科学技术研究所，即NMIJ/AIST）发布了四种矿物油标准物质（CRMs），分别为NMIJ CRM 7902-a、CRM 7903-a、CRM 7904-a和CRM 7905-a，用于多氯联苯（PCBs）的测定。这些标准物质的原料为绝缘油（CRM 7902-a和CRM 7903-a）和燃料油（CRM7904-a和CRM 7905-a）。将PCB3、PCB8以及包含四种氯丹的工业PCB产品的溶液添加到油基质中。添加了PCB的油（CRM 7902-a和CRM 7904-a）中PCB的总浓度约为6 mg kg(-1)。此外，未添加PCB的矿物油也作为标准物质分发（CRM 7903-a和CRM 7905-a）。NMIJ/AIST对这些标准物质进行了特性鉴定，使用了多种分析方法对矿物油和PCB溶液进行分析，如二甲基亚砜萃取、正相液相色谱、凝胶渗透色谱、反相液相色谱以及使用亚砜键合硅胶的色谱法；和/或用于气相色谱的各种毛细管柱，以及用于质谱的两种电离模式。矿物油中的目标化合物和PCB溶液中的目标化合物通过主要测量方法之一同位素稀释质谱法（ID-MS）进行测定。已给出了这些标准物质中11种PCB同系物（PCB3、8、28、52、101、118、138、153、180、194和206）的标准值。这些标准物质具有通过日本官方测定废弃物中PCBs的方法测定的PCB同系物浓度的信息值，以及使用振荡密度计测定的密度值。由于通过对标准物质对进行重量混合可以制备出PCB浓度在添加了PCB和未添加PCB的标准物质各自特性值之间任意取值的油样，因此这些标准物质可用于验证使用具有不同灵敏度各种仪器进行的PCB分析。
