Delatte H, Paupy C, Dehecq J S, Thiria J, Failloux A B, Fontenille D
UR 016, IRD, BP 64501, 34394 Montpellier 5, France.
Parasite. 2008 Mar;15(1):3-13. doi: 10.1051/parasite/2008151003.
Chikungunya virus (CHIKV) and dengue virus (DENV) are mosquito-borne viruses transmitted by the Aedes genus. Dengue is considered as the most important arbovirus disease throughout the World. Chikungunya, known from epidemics in continental Africa and Asia, has up to now been poorly studied. It has been recently responsible for the severe 2004-2007 epidemic reported in the Indian Ocean (IO), which has caused several serious health and economic problems. This unprecedented epidemic of the IO has shown severe health troubles with morbidity and death associated, which had never been observed before. The two major vectors of those arboviruses in the IO area are Aedes aegypti and Aedes albopictus. The latest is considered as the main vector in most of the islands of the area, especially in Reunion Island. Ae. albopictus showed strong ecological plasticity. Small disposable containers were the principal urban breeding sites, and preferred natural developmental sites were bamboo stumps and rock holes in peri-urban and gully areas. The virus has been isolated from field collected Ae. albopictus females, and in two out of 500 pools of larvae, demonstrating vertical transmission. Experimental works showed that both Ae. albopictus and Ae. aegypti from west IO islands are efficient vectors of dengue and chikungunya viruses. Since 2006 and all along the epidemic of CHIKV, measures for the control of larvae (temephos then Bacillus thuringiensis) and adults (fenitrothion, then deltamethrine) of Ae. albopictus where applied along with individual and collective actions (by the use of repellents, and removal of breeding sites around houses) in Reunion Island. In order to prevent such epidemics, a preventive plan for arboviruses upsurge is ongoing processed. This plan would allow a quicker response to the threat and adapt it according to the virus and its specific vector.
基孔肯雅病毒(CHIKV)和登革病毒(DENV)是由伊蚊属传播的蚊媒病毒。登革热被认为是全球最重要的虫媒病毒病。基孔肯雅热在非洲大陆和亚洲曾有过疫情报道,但迄今为止对其研究较少。最近它导致了2004 - 2007年印度洋(IO)地区的严重疫情,引发了一些严重的健康和经济问题。印度洋地区前所未有的这场疫情出现了严重的健康问题,伴有发病率和死亡率,这是以前从未见过的。印度洋地区这些虫媒病毒的两个主要传播媒介是埃及伊蚊和白纹伊蚊。后者被认为是该地区大多数岛屿的主要传播媒介,尤其是在留尼汪岛。白纹伊蚊表现出很强的生态可塑性。小型一次性容器是主要的城市滋生地,而城郊和沟壑地区首选的自然发育场所是竹桩和岩洞。已从野外采集的白纹伊蚊雌蚊中分离出该病毒,并且在500组幼虫中有两组检测到病毒,证明了垂直传播。实验研究表明,来自印度洋西部岛屿的白纹伊蚊和埃及伊蚊都是登革病毒和基孔肯雅病毒的有效传播媒介。自2006年以来,在基孔肯雅病毒疫情期间,留尼汪岛对白纹伊蚊的幼虫(先是使用双硫磷,然后是苏云金芽孢杆菌)和成蚊(先是使用杀螟硫磷,然后是溴氰菊酯)采取了控制措施,并结合了个人和集体行动(使用驱蚊剂以及清除房屋周围的滋生地)。为预防此类疫情,正在制定一项针对虫媒病毒激增的预防计划。该计划将能够对威胁做出更快的反应,并根据病毒及其特定传播媒介进行调整。