Park Hyun Sun, Park Eun Sang, Park Kyoung Chan, Cho Kwang Hyun, Youn Sang Woong
Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea.
J Dermatol. 2008 Apr;35(4):234-7. doi: 10.1111/j.1346-8138.2008.00451.x.
Chronic macrocheilia is a relatively rare condition of chronic lip enlargement. It can be cosmetically and functionally problematic, and often poses a diagnostic and therapeutic challenge to clinicians especially when its etiology is unclear. We describe a 40-year-old Korean man who presented with a 4-year history of lower lip swelling and was diagnosed as having chronic idiopathic macrocheilia after excluding other disease entities based on histopathological and clinical findings. We believe that the present case has a unique clinico-histopathological feature that differentiates it from other cases of chronic cheilitis, namely, simple lip swelling showing minor salivary gland hyperplasia only, suggesting the possibility of a new disease entity.
慢性巨唇症是一种相对罕见的慢性唇部肿大病症。它在外观和功能上都可能产生问题，并且常常给临床医生带来诊断和治疗方面的挑战，尤其是当病因不明时。我们描述了一名40岁的韩国男性，他有4年下唇肿胀的病史，根据组织病理学和临床检查结果排除其他疾病后，被诊断为慢性特发性巨唇症。我们认为，本病例具有独特的临床组织病理学特征，使其有别于其他慢性唇炎病例，即单纯唇部肿胀且仅伴有小唾液腺增生，提示可能存在一种新的疾病实体。
