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A complex plasma plant sterol locus on mouse chromosome 14 has at least two genes regulating intestinal sterol absorption.
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Overexpression of apolipoprotein A-I promotes reverse transport of cholesterol from macrophages to feces in vivo.
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Loci on chromosomes 14 and 2, distinct from ABCG5/ABCG8, regulate plasma plant sterol levels in a C57BL/6J x CASA/Rk intercross.
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Ezetimibe, a potent cholesterol absorption inhibitor, inhibits the development of atherosclerosis in ApoE knockout mice.
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Biliary cholesterol excretion: a novel mechanism that regulates dietary cholesterol absorption.
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