Suppr超能文献

健康猫和肥厚型心肌病猫的彩色M型组织多普勒成像

Colour M-mode tissue Doppler imaging in healthy cats and cats with hypertrophic cardiomyopathy.

作者信息

Koffas H, Dukes-McEwan J, Corcoran B M, Moran C M, French A, Sboros V, Simpson K, Anderson T, McDicken W N

机构信息

Department of Veterinary Clinical Studies, Royal (Dick) School of Veterinary Studies, Midlothian, EH25 9RG.

出版信息

J Small Anim Pract. 2008 Jul;49(7):330-8. doi: 10.1111/j.1748-5827.2008.00543.x.

Abstract

OBJECTIVES

To determine whether decreased diastolic and systolic myocardial velocity gradient between the endocardium and the epicardium exist in the left ventricle of cats with hypertrophic cardiomyopathy.

METHODS

Myocardial velocity gradient and mean myocardial velocities were measured by colour M-mode tissue Doppler imaging in the left ventricular free wall of 20 normal cats and 17 cats with hypertrophic cardiomyopathy.

RESULTS

The peak myocardial velocity gradient (sec(-1)) during the first (E1) (5.71+/-1.75 versus 11.38+/-3.1, P<0.001) and second phase (E2) (3.09+/-1.53 versus 7.02+/-3.1, P=0.005) of early diastole and also the maximum early diastolic myocardial velocity gradient (Emax) (6.12+/-2.1 versus 10.76+/-3.2, P<0.001) were reduced in cats with hypertrophic cardiomyopathy compared with normal cats. Peak myocardial velocity gradient during early systole (Se) was lower in affected cats than in normal cats (6.26+/-2.08 versus 8.67+/-2.83, P=0.006). Affected cats had a lower peak mean myocardial velocities (mm/s) during the two isovolumic periods (IVRb and IVCb) compared with normal cats (2.97+/-6.76 versus 12.74+/-5.5 and 22.28+/-9.96 versus 38.65+/-10.1, P<0.001, respectively).

CLINICAL SIGNIFICANCE

This study shows that hypertrophic cardiomyopathy cats have decreased myocardial velocity gradient during both diastole and systole and also altered myocardial motion during the two isovolumic periods. Myocardial velocity gradients recorded by colour M-mode tissue Doppler imaging can discriminate between the healthy and diseased myocardium.

摘要

目的

确定肥厚型心肌病猫的左心室心内膜与心外膜之间舒张期和收缩期心肌速度梯度是否降低。

方法

采用彩色M型组织多普勒成像技术,测量20只正常猫和17只肥厚型心肌病猫左心室游离壁的心肌速度梯度和平均心肌速度。

结果

与正常猫相比,肥厚型心肌病猫在舒张早期的第一阶段(E1)(5.71±1.75对11.38±3.1,P<0.001)和第二阶段(E2)(3.09±1.53对7.02±3.1,P=0.005)的峰值心肌速度梯度(秒-1)以及舒张早期最大心肌速度梯度(Emax)(6.12±2.1对10.76±3.2,P<0.001)均降低。肥厚型心肌病猫收缩早期的峰值心肌速度梯度(Se)低于正常猫(6.26±2.08对8.67±2.83,P=0.006)。与正常猫相比,肥厚型心肌病猫在两个等容期(IVRb和IVCb)的平均心肌峰值速度(毫米/秒)较低(分别为2.97±6.76对12.74±5.5以及22.28±9.96对38.65±10.1,P<0.001)。

临床意义

本研究表明,肥厚型心肌病猫在舒张期和收缩期的心肌速度梯度均降低,且在两个等容期的心肌运动也发生改变。彩色M型组织多普勒成像记录的心肌速度梯度可区分健康心肌和患病心肌。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验