Soslow Jonathan H, Friedberg Mark K, Silverman Norman H
Division of Pediatric Cardiology, Vanderbilt Children's Hospital, Nashville, Tennessee, USA.
Echocardiography. 2008 Jul;25(6):650-2. doi: 10.1111/j.1540-8175.2008.00667.x. Epub 2008 Apr 8.
Idiopathic intrauterine closure of the ductus arteriosus, distinct from intrauterine constriction associated with maternal NSAID ingestion or other secondary causes, is an uncommon event that often results in significant morbidity and mortality. We report on a 32-week fetus with meconium pseudocyst that presented with idiopathic intrauterine constriction of the ductus arteriosus, and review the literature. We suggest that early diagnosis and judicious obstetrical management, in conjunction with pediatric cardiology consultation based on serial fetal echocardiography, can lead to timely delivery and reversal of the pathophysiology providing the potential for a favorable outcome.
特发性动脉导管宫内闭合与因母亲摄入非甾体抗炎药或其他继发原因导致的宫内狭窄不同,是一种罕见事件,常导致严重的发病和死亡。我们报告一例32周胎儿,患有胎粪假囊肿,出现特发性动脉导管宫内狭窄,并复习相关文献。我们建议,基于系列胎儿超声心动图进行早期诊断和明智的产科管理,并结合儿科心脏病学会诊,可实现适时分娩并逆转病理生理过程,从而有可能获得良好结局。