Hadas L, Vosecková A, Duska F, Vizda J, Kafka P, Urbanová E
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove Suppl. 1991;34(5):561-70.
The distribution of coldfocal cardiopharmacological substance 99mTc-TBI has been studied on a total of 14 dogs in relation to the healthy heart tissue. The quality heart scan resulted from the use of 99mTc-TBI. It may be performed 30 min after the administration of mentioned substance, when its blood activity is smaller than 10% activity of myocardium From the other organs, the myocardium scan may be influenced negatively with only liver which achieves 200% activity of left heart ventricle what is evidently consequential in worse imaging of "lower" ischemic lesions. These results justify us to conclude that the 99mTc-TBI is a substance suitable for scintigraphical imaging of myocardium.
已对总共14只狗进行了研究，以探讨冷聚焦心脏药理学物质99mTc - TBI相对于健康心脏组织的分布情况。使用99mTc - TBI进行了高质量的心脏扫描。在给予上述物质30分钟后即可进行扫描，此时其血液活性低于心肌活性的10%。在其他器官中，只有肝脏可能对心肌扫描产生负面影响，肝脏的活性达到左心室活性的200%，这显然会导致“下部”缺血性病变的成像效果变差。这些结果使我们有理由得出结论，99mTc - TBI是一种适用于心肌闪烁成像的物质。
