副肿瘤性小脑变性作为乳腺癌的一种表现——病例报告及文献综述
Paraneoplastic cerebellar degeneration as a presentation of breast cancer - a case report and review of the literature.
作者信息
Noorani Alia, Sadiq Zaid, Minakaran Neda, Coleman Catherine, Thomas Val A, Mokbel Kefah
机构信息
Breast Surgery Unit, St George's Hospital NHS Trust, London, UK.
Department of Pathology, St George's Hospital NHS Trust, London, UK.
出版信息
Int Semin Surg Oncol. 2008 Apr 21;5:8. doi: 10.1186/1477-7800-5-8.
Paraneoplastic cerebellar degeneration is part of a rare spectrum of neurological syndromes whereby gynaecological, lung or breast cancers present primarily with neurological manifestations. The presence of onconeural antibodies and PET scanning help in the challenging diagnosis of these conditions but despite the treatment of the primary cancer, the prognosis for the neurological symptoms is poor.
副肿瘤性小脑变性是一种罕见的神经系统综合征，其中妇科、肺癌或乳腺癌主要表现为神经症状。肿瘤相关神经元抗体的存在和PET扫描有助于对这些疾病进行具有挑战性的诊断，但尽管对原发性癌症进行了治疗，神经症状的预后仍然很差。
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