Zouiten Othmane, Benbrahim Zineb, Amaadour Lamiae, Mellas Nawfel
Service d'Oncologie Médicale, CHU Hassan II, Route de Sidi Harazem, Fès, Morocco.
Pan Afr Med J. 2019 Aug 2;33:281. doi: 10.11604/pamj.2019.33.281.17711. eCollection 2019.
Paraneoplastic neurologic degeneration (PND) is characterized by acute and subacute onset neurological syndrome associated with active or with subclinical cancer. It is rare but early diagnosis can improve the neurological and carcinological prognosis. Among the PNDs it is possible to distinguish subacute cerebellar degeneration often associated with gynecological or breast cancer. We report the case of a 50-year old female patient on follow-up for ovarian adenocarcinoma treated with surgery and whose recurrence was detected due to anti-Yo antibody-positive subacute cerebellar degeneration.
副肿瘤性神经变性(PND)的特征是与活动性或亚临床癌症相关的急性和亚急性起病的神经综合征。它很罕见,但早期诊断可改善神经学和肿瘤学预后。在PND中,可以区分出常与妇科或乳腺癌相关的亚急性小脑变性。我们报告了一例50岁女性患者的病例,该患者因卵巢腺癌接受手术治疗并进行随访,因其抗Yo抗体阳性的亚急性小脑变性而检测到复发。