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未行抗反流手术的腹腔镜贲门肌切开术的症状性结局:最初40例的经验

Symptomatic outcome of laparoscopic cardiomyotomy without an antireflux procedure: experience in initial 40 cases.

作者信息

Parshad Rajinder, Hazrah Priya, Saraya Anoop, Garg Pramod, Makharia Govind

机构信息

Department of Surgery, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Surg Laparosc Endosc Percutan Tech. 2008 Apr;18(2):139-43. doi: 10.1097/SLE.0b013e318168db86.

Abstract

The aim of surgical treatment in achalasia cardia is symptom relief. Most studies have evaluated the results of laparoscopic cardiomyotomy with an antireflux procedure. However, data on the effectiveness of laparoscopic cardiomyotomy without an antireflux procedure is sparse. We describe our experience of laparoscopic cardiomyotomy without antireflux procedure in 40 consecutive patients with respect to symptom relief and complications. There was no mortality and 1 conversion. Preoperatively dysphagia, regurgitation, and heartburn were present in 40, 39, and 11 patients. At a mean follow-up of 26 months, there was a significant improvement in symptom scores. Two patients (5%) had persistent postoperative dysphagia. One improved on conservative therapy, whereas other was treated with relaparoscopic cardiomyotomy. Three patients (7.5%) developed heartburn in the postoperative period, which was well controlled with proton pump inhibitors. Laparoscopic cardiomyotomy without antireflux procedure results in excellent relief of dysphagia without producing significant symptomatic reflux in the follow-up.

摘要

贲门失弛缓症手术治疗的目的是缓解症状。大多数研究评估了腹腔镜贲门肌切开术联合抗反流手术的效果。然而,关于无抗反流手术的腹腔镜贲门肌切开术有效性的数据很少。我们描述了连续40例接受无抗反流手术的腹腔镜贲门肌切开术患者在症状缓解和并发症方面的经验。无死亡病例,1例中转手术。术前,40例、39例和11例患者分别存在吞咽困难、反流和烧心症状。平均随访26个月时,症状评分有显著改善。2例患者(5%)术后持续存在吞咽困难。1例经保守治疗后好转,另1例接受了再次腹腔镜贲门肌切开术治疗。3例患者(7.5%)术后出现烧心症状,使用质子泵抑制剂后得到良好控制。无抗反流手术的腹腔镜贲门肌切开术在随访中能有效缓解吞咽困难,且不会产生明显的症状性反流。

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