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腹腔镜下贲门肌切开术是否需要抗反流手术?

Does laparoscopic cardiomyotomy require an antireflux procedure?

作者信息

Kumar V, Shimi S M, Cuschieri A

机构信息

Dept. of Surgery, Ninewells Hospital and Medical School, University of Dundee, United Kingdom.

出版信息

Endoscopy. 1998 Jan;30(1):8-11. doi: 10.1055/s-2007-993720.

Abstract

BACKGROUND AND STUDY AIMS

There is controversy concerning the need for an antireflux procedure in patients undergoing open or endoscopic cardiomyotomy for achalasia. The addition of an antireflux wrap (partial or total), while preventing reflux, may result in persistence or incomplete relief of dysphagia in patients with total oesophageal aperistalsis. The technique of laparoscopic cardiomyotomy used in Dundee preserves the lateral and posterior attachments of the gastro-oesophageal junction, and was designed to minimize the risk of gastro-oesophageal reflux.

PATIENTS AND METHODS

A consecutive series of patients with achalasia (n = 19) were treated by laparoscopic cardiomyotomy using the Dundee technique, which limits the mobilization to the anterior wall of the abdominal and thoracic oesophagus. The patients were followed up prospectively to assess the long-term relief of dysphagia and the postoperative incidence of reflux symptoms, with or without oesophagitis.

RESULTS

The follow-up symptoms and assessment of the patients (15-53 months, median 27 months) showed total relief (n = 12) or substantial relief (n = 5) of dysphagia in 89%. On assessment at a median follow-up of 27 months, the number of patients experiencing heartburn after this operation increased from four of 15 to five of 15, and one patient (6.6%) developed endoscopically proved oesophagitis, with a positive oesophageal pH monitoring test.

CONCLUSIONS

The routine addition of an antireflux operation is not justified in patients undergoing laparoscopic cardiomyotomy, provided that the lateral and posterior attachment of the oesophagus are kept intact.

摘要

背景与研究目的

对于接受贲门失弛缓症开放或内镜下贲门肌切开术的患者是否需要抗反流手术存在争议。增加抗反流包绕术(部分或完全)虽然可预防反流,但可能导致食管完全无蠕动的患者吞咽困难持续存在或缓解不完全。邓迪采用的腹腔镜贲门肌切开术保留了胃食管交界处的外侧和后侧附着结构,旨在将胃食管反流风险降至最低。

患者与方法

连续纳入19例贲门失弛缓症患者,采用邓迪技术行腹腔镜贲门肌切开术,该技术将食管腹段和胸段前壁的游离限制在一定范围。对患者进行前瞻性随访,以评估吞咽困难的长期缓解情况以及反流症状(无论有无食管炎)的术后发生率。

结果

患者随访症状及评估(15 - 53个月,中位时间27个月)显示,89%的患者吞咽困难完全缓解(n = 12)或显著缓解(n = 5)。在中位随访27个月时评估,术后出现烧心的患者数量从15例中的4例增至15例中的5例,1例患者(6.6%)经内镜证实发生食管炎,食管pH监测试验呈阳性。

结论

对于接受腹腔镜贲门肌切开术的患者,只要食管的外侧和后侧附着结构保持完整,常规附加抗反流手术并无必要。

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