Ohashi Y, Nakai Y
Department of Otolaryngology, Osaka City University Medical School, Japan.
Acta Otolaryngol Suppl. 1991;486:149-61. doi: 10.3109/00016489109134992.
From a survey of the literature on mucociliary function in the tubotympanum, it is clear that mucociliary activity and ciliary activity are deeply involved in the pathogenesis, pathology, and prognosis of otitis media with effusion. Ciliary function in the middle ear, especially in the tympanic orifice and the Eustachian tube, has an important role in the mucociliary clearance of surplus secretion to the pharynx. Our review demonstrates that ciliary activity in the tubotympanum is sensitive to a variety of pathological agents including bacteria, bacterial endotoxin, irritant gases, and irradiation, resulting in mucociliary dysfunction of the tubotympanum.
通过对有关鼓室-咽鼓管黏膜纤毛功能的文献进行调研可知，黏膜纤毛活动和纤毛活动与分泌性中耳炎的发病机制、病理及预后密切相关。中耳的纤毛功能，尤其是鼓膜开口处和咽鼓管的纤毛功能，对于将多余分泌物通过黏膜纤毛清除至咽部起着重要作用。我们的综述表明，鼓室-咽鼓管的纤毛活动对包括细菌、细菌内毒素、刺激性气体及辐射在内的多种致病因素敏感，从而导致鼓室-咽鼓管的黏膜纤毛功能障碍。
