Takahashi Naoki, Hartman Robert P, Vrtiska Terri J, Kawashima Akira, Primak Andrew N, Dzyubak Oleksandr P, Mandrekar Jayawant N, Fletcher Joel G, McCollough Cynthia H
Department of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, USA.
AJR Am J Roentgenol. 2008 May;190(5):1169-73. doi: 10.2214/AJR.07.3154.
The objective of our study was to evaluate the feasibility of virtual unenhanced images reconstructed from a dual-energy CT scan to depict urinary stones in an iodine solution in a phantom study.
Twenty urinary stones of different sizes (1.4-4.2 mm in short-axis diameter) were placed in plastic containers. The containers were consecutively filled with different concentrations of iodine solution (21, 43, 64, 85, and 107 mg/dL; CT attenuation value range, 510-2,310 H at 120 kVp). Dual-energy CT was repeated with 80-140 and 100-140 kVp pairs, two collimation-slice thickness combinations, and the presence or absence of a 4-cm-thick oil gel around the phantom. The iodine-subtraction virtual unenhanced images were reconstructed using commercial software. The images were evaluated by three radiologists in consensus for the visibility of the stones and the presence of residual nonsubtracted iodine. Stone visibility rates were compared between the 80-140 and 100-140 kVp pairs and the five different iodine concentrations.
Stone visibility rates with the 80-140 kVp pair were 99%, 93%, 96%, 94%, and 3% and those with the 100-140 kVp pair were 98%, 95%, 99%, 94%, and 99% for an iodine concentration of 21, 43, 64, 85, and 107 mg/dL, respectively. The poor visibility rate with 80-140 kVp and 107 mg/dL iodine concentration was due to the failure of iodine subtraction.
Dual-energy CT iodine-subtraction virtual unenhanced technique is capable of depicting urinary stones in iodine solutions of a diverse range of concentrations in a phantom study.
本研究的目的是在体模研究中评估从双能CT扫描重建的虚拟平扫图像描绘碘溶液中尿路结石的可行性。
将20颗不同大小(短轴直径1.4 - 4.2毫米)的尿路结石放置在塑料容器中。容器依次填充不同浓度的碘溶液(21、43、64、85和107毫克/分升;在120千伏峰值时CT衰减值范围为510 - 2310亨氏单位)。使用80 - 140千伏峰值和100 - 140千伏峰值对、两种准直切片厚度组合以及体模周围有无4厘米厚的油凝胶重复进行双能CT检查。使用商业软件重建碘减影虚拟平扫图像。由三位放射科医生共同评估图像中结石的可见性以及残留未减影碘的存在情况。比较80 - 140千伏峰值对和100 - 140千伏峰值对以及五种不同碘浓度下的结石可见率。
对于碘浓度为21、43、64、85和107毫克/分升的情况,80 - 140千伏峰值对的结石可见率分别为99%、93%、96%、94%和3%,100 - 140千伏峰值对的结石可见率分别为98%、95%、99%、94%和99%。80 - 140千伏峰值和107毫克/分升碘浓度时可见率较低是由于碘减影失败。
在体模研究中,双能CT碘减影虚拟平扫技术能够描绘不同浓度碘溶液中的尿路结石。