Kim Bum Soo, Ahn Kook Jin, Park Young Hak, Hahn Seong Tai
Department of Radiology, Kangnam St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
AJR Am J Roentgenol. 2008 May;190(5):1376-9. doi: 10.2214/AJR.07.2778.
The purpose of this study was to determine the effectiveness of laryngeal phonation CT for the diagnosis of vocal cord paralysis by examining the physiologic and functional changes in the larynx during vowel phonation in patients with vocal cord paralysis.
For the control study, three healthy volunteers underwent laryngeal phonation CT while vocalizing the vowels /hee/, /ih/, and /ah/, and reconstructed coronal images of the larynx were obtained. After the control study, 28 patients with unilateral vocal cord paralysis underwent laryngeal phonation CT during /hee/ phonation, which was chosen as a most appropriate vowel for this purpose. Changes in the paralyzed and normal vocal cords were evaluated quantitatively and qualitatively on coronal reconstruction images.
On the coronal reconstructed images from the healthy volunteers, the normal cords had a shoulder formation appearance, and the cords lay within 1 mm lateral to the midline during phonation. For patients with vocal cord paralysis during /hee/ phonation, the average angle formed by the long axis of the vocal cord and the midline was 71.67 degrees on the affected side and 92.21 degrees on the normal side (p = 0.001). The vocal cord edges lay 1.5 mm lateral to the midline on the affected side and 0.44 mm lateral to the midline on the normal side (p = 0.003). In the qualitative study, the two observers found the coronal reconstructions of the laryngeal phonation CT scans yielded a higher detection rate than did conventional axial CT.
Laryngeal phonation CT proved more useful for evaluating vocal cord paralysis than did conventional CT and can be used as a primary diagnostic tool when vocal cord paralysis is suspected.
本研究的目的是通过检查声带麻痹患者在元音发声时喉部的生理和功能变化,确定喉部发声CT对声带麻痹的诊断有效性。
在对照研究中,三名健康志愿者在发元音/hee/、/ih/和/ah/时接受喉部发声CT检查,并获得喉部的冠状位重建图像。对照研究后,28名单侧声带麻痹患者在发/hee/音时接受喉部发声CT检查,该元音被选为最适合此项检查的元音。在冠状位重建图像上对麻痹侧和正常侧声带的变化进行定量和定性评估。
在健康志愿者的冠状位重建图像上,正常声带呈现肩部形成外观,发声时声带位于中线外侧1毫米范围内。对于在发/hee/音时出现声带麻痹的患者,患侧声带长轴与中线形成的平均角度为71.67度,正常侧为92.21度(p = 0.001)。患侧声带边缘位于中线外侧1.5毫米处,正常侧位于中线外侧0.44毫米处(p = 0.003)。在定性研究中,两名观察者发现喉部发声CT扫描的冠状位重建比传统轴位CT具有更高的检出率。
喉部发声CT在评估声带麻痹方面比传统CT更有用,当怀疑有声带麻痹时可作为主要诊断工具。