Avci C, Avtan L
Service de Chirurgie générale de la Faculté de médecine, Université d'Istambul, Ist Tip Fakultesi, Genel Cerrahi, Turquie.
Chirurgie. 1991;117(8):653-9; discussion 660.
Free jejunal graft autotransplantation for reconstruction of pharyngoesophageal defects was performed in 27 cases between 1983 and 1990. Of 27 cases, 26 patients who had carcinoma of hypopharynx underwent pharyngo-laryngo-cervical esophagectomy and interposition of free jejunal autograft. In one case who had a small and early-staged carcinoma of the cervical esophagus underwent resection of the cervical esophagus without laryngectomy and free jejunal autotransplantation in order to preserve the continuity of the alimentary tract. In the first 5 cases, the autografts interpositioned in the neck had single pedicle and were revascularized by one artery and vein, like the applications in the literature. Two fistulas and one necrosis were observed in these patients. In the following 22 patients a new model of free graft was applied. Jejunal graft prepared with double pedicles in abdomen was interpositioned in the neck with the microvascular anastomosis of the 4 vessels (two arteries and two veins) belonging to both pedicles. It was observed that the blood supply and vitality of the double pedicled jejunal graft was better comparing to the jejunal graft with single pedicle. Also, the feasibility of +4 degrees C continuous perfusion from the second pedicle protected the grafts from warm ischaemia. Only one case developed a fistula and no necrosis was observed in the 22 cases with double pedicled free jejunal autografts. These results suggested that application of double pedicled jejunal grafts reduces the risk of fistula and necrosis, despite the total operation time is 45-60 minutes longer.
1983年至1990年间,对27例患者实施了游离空肠移植自体移植术以重建咽食管缺损。27例患者中,26例下咽癌患者接受了下咽-喉-颈段食管切除术并植入游离空肠自体移植物。1例颈段食管早期小癌患者,未行喉切除术,仅切除颈段食管并进行游离空肠自体移植,以保持消化道的连续性。在前5例患者中,植入颈部的自体移植物为单蒂,通过一条动脉和一条静脉进行血管重建,如同文献中的应用。这些患者中观察到2例瘘管和1例坏死。在随后的22例患者中,应用了一种新的游离移植模型。在腹部制备双蒂空肠移植物,将其植入颈部,并对属于两个蒂的4条血管(两条动脉和两条静脉)进行微血管吻合。观察到双蒂空肠移植物的血供和活力比单蒂空肠移植物更好。此外,从第二个蒂进行4℃持续灌注的可行性保护了移植物免受热缺血的影响。在22例双蒂游离空肠自体移植患者中,仅1例出现瘘管,未观察到坏死。这些结果表明,尽管总手术时间延长45 - 60分钟,但应用双蒂空肠移植物可降低瘘管和坏死的风险。