Ong Constantine T T, Ivanovski Saso, Needleman Ian G, Retzepi Maria, Moles David R, Tonetti Maurizio S, Donos Nikolaos
Unit of Periodontology & International Centre for Evidence-Based Oral Health, UCL Eastman Dental Institute, London, UK.
J Clin Periodontol. 2008 May;35(5):438-62. doi: 10.1111/j.1600-051X.2008.01207.x.
To determine implant outcomes in partially dentate patients who have been treated for periodontitis compared with periodontally healthy patients.
All longitudinal studies (until March 2006) of endosseous dental implants of at least 6 months of loading were searched. Studies presented with one or more of the outcome measures (implant survival, success, bone-level change, peri-implantitis) were included. Screening, data abstraction and quality assessment were conducted independently and in duplicate.
From 4448 citations, 546 full-text papers were screened and nine studies were included. Overall, the non-periodontitis patients demonstrated better outcomes than treated periodontitis patients. However, the strength of evidence showed that the studies included were at a medium to high risk of bias, with lack of appropriate reporting and analysis of outcomes plus lack of accounting for confounders, especially smoking. Furthermore, the studies showed variability in the definitions of treated and non-periodontitis, outcome criteria and quality of supportive periodontal therapy. Meta-analysis could not be performed due to heterogeneity of the chief study characteristics.
There is some evidence that patients treated for periodontitis may experience more implant loss and complications around implants than non-periodontitis patients. Evidence is stronger for implant survival than implant success; methodological issues limit the potential to draw robust conclusions.
确定与牙周健康患者相比,接受过牙周炎治疗的部分牙列缺损患者的种植体治疗效果。
检索了所有关于骨内牙种植体且加载时间至少6个月的纵向研究(截至2006年3月)。纳入呈现一项或多项结局指标(种植体存留、成功、骨水平变化、种植体周围炎)的研究。筛查、数据提取和质量评估由两人独立进行。
从4448篇文献中,筛选出546篇全文论文,纳入9项研究。总体而言,非牙周炎患者的治疗效果优于接受过牙周炎治疗的患者。然而,证据强度表明,纳入的研究存在中到高度的偏倚风险,存在结局报告和分析不恰当以及未考虑混杂因素(尤其是吸烟)的问题。此外,研究在接受治疗和未患牙周炎的定义、结局标准以及支持性牙周治疗质量方面存在差异。由于主要研究特征的异质性,无法进行荟萃分析。
有证据表明,与非牙周炎患者相比,接受过牙周炎治疗的患者可能种植体丢失更多,种植体周围并发症更多。关于种植体存留的证据比种植体成功的证据更强;方法学问题限制了得出可靠结论的可能性。