Chen Jeon-Hor, Liu Hui, Baek Hyeon-Man, Nalcioglu Orhan, Su Min-Ying
Tu and Yuen Center for Functional Onco-Imaging, University of California, Irvine, CA 92697-5020, USA.
Magn Reson Imaging. 2008 Nov;26(9):1207-14. doi: 10.1016/j.mri.2008.02.004. Epub 2008 Apr 23.
Studies specifically reporting MRI of fibrocystic change (FCC) of the breast are very few and its MRI features are not clearly known. The purpose of this study was to analyze the MRI features of FCC of the breast.
Thirty-one patients with pathologically proven FCC of the breast were retrospectively reviewed. The MRI study was performed using a 1.5-T MR scanner with standard bilateral breast coil. The imaging protocol consisted of pre-contrast T1-weighed imaging and dynamic contrast-enhanced axial T1-weighed imaging. The MRI features were interpreted based on the morphologic and enhancement kinetic descriptors defined on ACR BIRADS-MRI lexicon.
FCC of the breast had a wide spectrum of morphologic and kinetic features on MRI. Two types of FCC were found, including a more diffuse type of nonmass lesion (12/31, 39%) showing benign enhancement kinetic pattern with medium wash-in in early phase (9/10, 90%) and a focal mass-type lesion (11/31, 35%) with enhancement kinetic usually showing rapid up-slope mimicking a breast cancer (8/11, 73%).
MRI is able to elaborate the diverse imaging features of FCC of the breast. Our result showed that FCC presenting as a focal mass-type lesion was usually overdiagnosed as malignancy. Understanding MRI of FCC is important to determine which cohort of patients should be followed up alone or receive aggressive management.
专门报道乳腺纤维囊性变（FCC）MRI表现的研究非常少，其MRI特征尚不清楚。本研究的目的是分析乳腺FCC的MRI特征。
回顾性分析31例经病理证实为乳腺FCC的患者。使用配备标准双侧乳腺线圈的1.5-T MR扫描仪进行MRI检查。成像方案包括对比剂前T1加权成像和动态对比增强轴向T1加权成像。根据ACR BIRADS-MRI词典中定义的形态学和增强动力学描述符对MRI特征进行解读。
乳腺FCC在MRI上具有广泛的形态学和动力学特征。发现了两种类型的FCC，包括一种更弥漫的非肿块性病变（12/31，39%），在早期表现为良性增强动力学模式，呈中等程度的早期强化（9/10，90%），以及一种局灶性肿块型病变（11/31，35%），其增强动力学通常表现为快速上升，类似乳腺癌（8/11，73%）。
MRI能够详细显示乳腺FCC的多种影像学特征。我们的结果表明，表现为局灶性肿块型病变的FCC通常被过度诊断为恶性肿瘤。了解FCC的MRI表现对于确定哪些患者群体应单独随访或接受积极治疗非常重要。
