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[肺癌患者血清中铁蛋白水平]

[Levels of ferritin in serum of patients with lung cancer].

作者信息

Sakowicz A, Kwiek S, Wiatr E

机构信息

III Kliniki Gruźlicy i Chorób Płuc, Instytutu Gruźlicy i Chorób Płuc, Warszawie.

出版信息

Pneumonol Alergol Pol. 1991;59(9-10):38-42.

PMID:1843645
Abstract

Serum ferritin levels using the radiometric method were determined in 161 lung cancer patients and in 50 patients with non-malignant pulmonary disorders. Elevated serum ferritin levels were seen more often in lung cancer patients (82%) than in those with the non-malignant disorders (52%). The levels of ferritin were also affected by the extension of the disease. In patients with stage III and IV serum ferritin levels were more pronounced (median 577 ng/ml) in comparison with stage I and II (300 ng/ml). Determination of serum ferritin levels may help in evaluating disease progression and staging, but can not be used as a screening test due to a low specificity.

摘要

采用放射免疫法测定了161例肺癌患者和50例非恶性肺部疾病患者的血清铁蛋白水平。肺癌患者血清铁蛋白水平升高的情况(82%)比非恶性疾病患者(52%)更常见。铁蛋白水平也受疾病进展程度的影响。与Ⅰ期和Ⅱ期患者(300 ng/ml)相比,Ⅲ期和Ⅳ期患者的血清铁蛋白水平更高(中位数为577 ng/ml)。血清铁蛋白水平的测定可能有助于评估疾病进展和分期,但由于特异性较低,不能用作筛查试验。

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