Gaertner U, Johannes K J
MMW Munch Med Wochenschr. 1976 Sep 3;118(36):1127-30.
The effect of essential phospholipids in combination with Clofibrate (N 041) was compared with that of Clofibrate alone in a double blind study in 96 patients with hypertriglyceridemia and/or hypercholesterolemia. The serum triglycerides fell more markedly with N 041 than with Clofibrate therapy alone. The greater cholesterol-lowering effect of N 041 was significant after treatment lasting 3 weeks and just failed to reach the 5% significance level after 6 weeks. Both preparations were well tolerated.
在一项针对96名高甘油三酯血症和/或高胆固醇血症患者的双盲研究中,将必需磷脂与氯贝特(N 041)联合使用的效果与单独使用氯贝特的效果进行了比较。与单独使用氯贝特治疗相比,使用N 041治疗后血清甘油三酯下降更为明显。N 041更大的降胆固醇作用在治疗3周后具有显著意义,而在6周后仅未能达到5%的显著水平。两种制剂耐受性均良好。