Castillo C, Herrera G, Gattas V, Riumallo J, Jarpa S, Alliende F
Instituto de Nutrición y Tecnología de los Alimentos (INTA), Universidad de Chile.
Rev Chil Pediatr. 1991 Jan-Feb;62(1):8-13.
Nitrogen, fat and energy retention were measured in 10 male infants (mean age = 6.8 mo) recovering from marasmic malnutrition while they were fed with either cow's milk based formula (LP) or a modified cow's milk formula (LPM). Their mean weight for age ratio was 72% and their weight for length ratio was 95% (NCHS standards). They went through two consecutive balance periods of 6 days each (3 d. for adaptation and 3 d. for urine and feces collection) beginning with either formula randomly. Both formulas had 85 kcal/dl with 11% protein calories in LPM and 13% in LP. Energy intake, absorption and relative retention were slightly greater with LPM than LP. Fat intake was greater under LPM than LP (5.4 vs. 4.5 g-kg-d, p < 0.025), which resulted in significant differences in fat absorption (LPM 4.3 vs. LP 3 g-kg-d, p < 0.025). Nitrogen intake was significantly lower under LPM than LP (487 vs. 571 mg-kg-d, p < 0.025) with lower urinary nitrogen excretion for LPM than for LP (304 vs. 417 mg-kg-d, p < 0.001). Apparent nitrogen retention averaged 115 mg-kg-d for LPM and only 69 mg-kg-d for LP (NS). A significant correlation was observed between nitrogen intake and nitrogen retention: r = 0.70 (y = 0.57x -167; p < 0.05) with LPM, and r = 0.77 (y = 0.63x -291, p < 0.01) with LP. A correlation was also found between energy intake and weight gain: r = 0.55 (NS) with LPM, and r = 0.88 (y = 0.26x -26; p < 0.001) with LP.(ABSTRACT TRUNCATED AT 250 WORDS)
对10名患有消瘦型营养不良且正在康复的男婴（平均年龄6.8个月）进行了氮、脂肪和能量潴留的测量，这些婴儿分别喂食基于牛奶的配方奶粉（LP）或改良牛奶配方奶粉（LPM）。他们的年龄别平均体重比为72%，身长别体重比为95%（美国国家卫生统计中心标准）。他们随机从一种配方奶粉开始，经历两个连续的为期6天的平衡期（3天适应期和3天尿液及粪便收集期）。两种配方奶粉每分升均含85千卡热量，LPM中蛋白质热量占11%，LP中占13%。与LP相比，LPM的能量摄入、吸收和相对潴留略高。LPM组的脂肪摄入量高于LP组（5.4对4.5克/千克/天，p<0.025），这导致脂肪吸收存在显著差异（LPM为4.3对LP为3克/千克/天，p<0.025）。LPM组的氮摄入量显著低于LP组（487对571毫克/千克/天，p<0.025），LPM组的尿氮排泄低于LP组（304对417毫克/千克/天，p<0.001）。LPM组的表观氮潴留平均为115毫克/千克/天，LP组仅为69毫克/千克/天（无显著差异）。观察到LPM组氮摄入量与氮潴留之间存在显著相关性：r = 0.70（y = 0.57x -167；p<0.05），LP组r = 0.77（y = 0.63x -291，p<0.01）。还发现能量摄入与体重增加之间存在相关性：LPM组r = 0.55（无显著差异），LP组r = 0.88（y = 0.26x -26；p<0.001）。（摘要截短于250字）
