Gerber Bernhard L, Raman Subha V, Nayak Krishna, Epstein Frederick H, Ferreira Pedro, Axel Leon, Kraitchman Dara L
Department of Cardiovascular Diseases, Cliniques Universitaires St Luc, Université Catholique de Louvain, Brussels, Belgium.
J Cardiovasc Magn Reson. 2008 Apr 28;10(1):18. doi: 10.1186/1532-429X-10-18.
In less than two decades, first-pass perfusion cardiovascular magnetic resonance (CMR) has undergone a wide range of changes with the development and availability of improved hardware, software, and contrast agents, in concert with a better understanding of the mechanisms of contrast enhancement. The following review provides a perspective of the historical development of first-pass CMR, the developments in pulse sequence design and contrast agents, the relevant animal models used in early preclinical studies, the mechanism of artifacts, the differences between 1.5T and 3T scanning, and the relevant clinical applications and protocols. This comprehensive overview includes a summary of the past clinical performance of first-pass perfusion CMR and current clinical applications using state-of-the-art methodologies.
在不到二十年的时间里，随着硬件、软件和造影剂的改进与普及，以及对造影剂增强机制的深入理解，首过灌注心血管磁共振成像（CMR）发生了诸多变化。以下综述介绍了首过CMR的历史发展、脉冲序列设计和造影剂的进展、早期临床前研究中使用的相关动物模型、伪影机制、1.5T和3T扫描的差异，以及相关的临床应用和方案。这一全面概述包括首过灌注CMR过去的临床性能总结以及当前使用先进方法的临床应用情况。
