Nielsen Michael Møller, Mortensen Anne, Sørensen Jakob Kierstein, Simonsen Ole, Graven-Nielsen Thomas
College-of-Health, Aalborg, Department of Physiotherapy, Selma Lagerloefs Vej 2, 9220 Aalborg East, Denmark.
Man Ther. 2009 Feb;14(1):101-9. doi: 10.1016/j.math.2007.12.008. Epub 2008 Apr 28.
The analgesic effects of passive movements on deep-tissue pain have not been sufficiently explored in human studies. The purpose of this study was to examine the effect of passive physiological movements (PPMs) on deep-tissue pain sensitivity. Seventeen healthy subjects were included in this randomised crossover study. In one session an electrically driven bicycle performed 30 min PPM of the knee joint. Another session without PPM served as control. The effect of PPM on experimental muscle pain was assessed. Muscle pain was induced by i.m. injection of hypertonic saline into the tibialis anterior muscle and the pain intensity was scored on an electronic visual analogue scale (VAS). The pressure pain sensitivity was assessed by recording of pressure pain thresholds (PPTs). McGill Pain Questionnaire (MPQ) was used to describe the quality of the induced pain. Compared with the control session PPM demonstrated: (1) a reduction of the experimental muscle pain intensity (VAS area and peak) and duration (17-31%, P<0.03), (2) lower MPQ score and a change in quality profile of experimental muscle pain (25%, P<0.01) and (3) an increased PPT (17%, P<0.0005). The present study demonstrated that PPM produced an immediate analgesic effect on deep-tissue pain indicating a possible involvement of neural inhibitory mechanisms.
被动运动对深部组织疼痛的镇痛作用在人体研究中尚未得到充分探索。本研究的目的是检验被动生理运动（PPM）对深部组织疼痛敏感性的影响。17名健康受试者纳入了这项随机交叉研究。在一个试验环节中，电动自行车对膝关节进行30分钟的PPM。另一个无PPM的试验环节作为对照。评估了PPM对实验性肌肉疼痛的影响。通过向胫骨前肌肌内注射高渗盐水诱发肌肉疼痛，并在电子视觉模拟量表（VAS）上对疼痛强度进行评分。通过记录压力痛阈值（PPT）评估压力痛敏感性。使用麦吉尔疼痛问卷（MPQ）描述诱发疼痛的性质。与对照试验环节相比，PPM表现出：（1）实验性肌肉疼痛强度（VAS面积和峰值）和持续时间降低（17%-31%，P<0.03），（2）MPQ评分更低，实验性肌肉疼痛的性质特征发生变化（25%，P<0.01），以及（3）PPT升高（17%，P<0.0005）。本研究表明，PPM对深部组织疼痛产生即时镇痛作用，提示神经抑制机制可能参与其中。
