Biederman Joseph, Petty Carter R, Doyle Alysa E, Spencer Thomas, Henderson Carly S, Marion Bryan, Fried Ronna, Faraone Stephen V
Pediatric Psychopharmacology Program of the Psychiatry Department, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
Dev Neuropsychol. 2008;33(1):44-61. doi: 10.1080/87565640701729755.
Neuropsychological deficits in the executive system are major sources of morbidity in individuals with attention-deficit/hyperactivity disorder (ADHD). We conducted a 5-year longitudinal study of girls with (N = 140) and without (N = 122) ADHD, aged 6-18 years at baseline. Neuropsychological functioning was assessed using standard neuropsychological testing assessing executive functions (EFs). Girls with ADHD were significantly more impaired than controls in all neuropsychological domains except set shifting. Despite variability in the stability of individual domains of EFs, the majority (79%) of girls with ADHD that met the categorical definition of executive function deficits (EFDs, defined as two or more EF tasks impaired) at baseline continued to have EFDs at the five-year followup. These findings document the stability of EFDs in girls with ADHD from childhood into adolescence.
执行系统中的神经心理缺陷是注意缺陷多动障碍（ADHD）患者发病的主要原因。我们对基线年龄在6至18岁的患有ADHD（N = 140）和未患ADHD（N = 122）的女孩进行了一项为期5年的纵向研究。使用评估执行功能（EFs）的标准神经心理学测试来评估神经心理功能。除了任务转换外，患有ADHD的女孩在所有神经心理学领域的受损程度均显著高于对照组。尽管EFs各个领域的稳定性存在差异，但在基线时符合执行功能缺陷（EFDs，定义为两项或更多EF任务受损）分类定义的ADHD女孩中，大多数（79%）在五年随访时仍有EFDs。这些发现证明了患有ADHD的女孩从童年到青春期EFDs的稳定性。
Zotero 插件