Kuloğlu Figen, Celik' Aygül Doğan, Yuluğkural Zerrin, Erkan Tülay, Keskin Serap, Akata Filiz
Trakya Universitesi Tip Fakültesi, Klinik Bakteriyoloji ve Infeksiyon Hastaliklari Anabilim Dali, Edirne.
Mikrobiyol Bul. 2008 Jan;42(1):137-42.
After the detection of human cases of highly pathogenic avian influenza A (H5N1) virus in Eastern Turkey in January 2006, Turkish Ministry of Health has had declared "National Plans of Activity for Pandemic Influenza". All health-care facilities were recommended to develop contingency plans. Then the essential activities were started in August 2006 in Trakya University, Faculty of Medicine (Edirne, Trace region of Turkey), and institutional education about pandemic influenza and preventive measures was implemented to health care workers (HCWs). In November 2006, health care workers were offered inactivated flu vaccine (Vaxigrip, Sanofi Pasteur, France) supplied by the Ministry of Health. The aim of this questionary survey was to evaluate the visions and conceptions of health care workers about influenza vaccination during the vaccination campaign. All the participants were informed by using an information form including the indications, contraindications and possible adverse reactions of flu vaccine, and were requested to complete the questionnaire about influenza vaccination according to their own perception before vaccination. Vaccine recipients were also invited to the vaccination unit if they had any adverse reaction. A total of 1041 HCWs (560 female, 481 male; mean age: 32.8 +/- 8.2 years) completed the questionnaire. Of them 884 subjects (85%) have accepted to be vaccinated, while 157 subjects (15%) have not. It was determined that 72 HCWs (6.9%) had been administered flu vaccine in 2005, and 38 (3.7%) have had an underlying chronic disease requiring medical therapy. Six subjects (16%) with an underlying chronic disease were vaccinated in 2005, while 66 HCWs (6.6%) without any chronic disease received vaccination voluntarily. Seven workers (0.7%) declined vaccination as they defined hypersensitivity to egg, and 84 workers (8%) had influenza vaccine voluntarily before the campaign in 2006. Sixty six workers (6.3%) have refused to be vaccinated as they considered influenza vaccination ineffective to protect against flu. Two workers (0.2%) had allergic skin reactions such as erythema and itching after vaccination. It can be concluded that influenza vaccination of the health care workers is a part of infection control policies and it is also a matter of patient safety. The implementation of necessary education programmes and attempts to emphasize the importance of vaccination of health care workers especially dealing with high risk patients, would be of crucial importance to decrease the morbidity and mortality due to influenza infections.
2006年1月在土耳其东部检测到人类感染高致病性甲型禽流感（H5N1）病毒病例后，土耳其卫生部宣布了“大流行性流感国家行动计划”。建议所有医疗保健机构制定应急计划。随后，2006年8月在土耳其特拉布宗大学医学院（埃迪尔内，土耳其色雷斯地区）启动了重要活动，并对医护人员实施了关于大流行性流感及预防措施的机构教育。2006年11月，向医护人员提供了由卫生部供应的灭活流感疫苗（Vaxigrip，赛诺菲巴斯德公司，法国）。本次问卷调查的目的是评估在疫苗接种活动期间医护人员对流感疫苗接种的看法和观念。通过使用一份包含流感疫苗的适应症、禁忌症和可能的不良反应的信息表告知所有参与者，并要求他们在接种疫苗前根据自己的认知填写关于流感疫苗接种的问卷。如果疫苗接种者有任何不良反应，也会被邀请到接种单位。共有1041名医护人员（560名女性，481名男性；平均年龄：32.8±8.2岁）完成了问卷。其中884名受试者（85%）接受了疫苗接种，而157名受试者（15%）未接种。经确定，72名医护人员（6.9%）在2005年接种过流感疫苗，38名（3.7%）患有需要药物治疗的基础慢性病。6名患有基础慢性病的受试者（16%）在2005年接种了疫苗，而66名无任何慢性病的医护人员（6.6%）自愿接种了疫苗。7名工作人员（0.7%）因对鸡蛋过敏而拒绝接种，84名工作人员（8%）在2006年活动前曾自愿接种过流感疫苗。66名工作人员（6.3%）因认为流感疫苗接种对预防流感无效而拒绝接种。2名工作人员（0.2%）在接种后出现了如红斑和瘙痒等过敏性皮肤反应。可以得出结论，医护人员的流感疫苗接种是感染控制政策的一部分，也是患者安全的问题。实施必要的教育计划并努力强调医护人员尤其是接触高风险患者的医护人员接种疫苗的重要性，对于降低流感感染导致的发病率和死亡率至关重要。
