Institute of Medical Microbiology and Infection Control, Hospital of the Johann Wolfgang Goethe-University, Frankfurt, Germany.
Euro Surveill. 2011 Apr 28;16(17):19854.
The emergence of the influenza A(H1N1)2009 virus provided a major challenge to health services around the world. However, vaccination rates for the public and for healthcare workers (HCWs) have remained low. We performed a study to review the reasons put forward by HCWs to refuse immunisation with the pandemic vaccine in 2009/10 and characterise attitudes in the influenza season 2010/11 due to the emergence of influenza A(H1N1)2009. A survey among HCWs and medical students in the clinical phase of their studies was conducted, using an anonymous questionnaire, at a German university hospital during an influenza vaccination campaign. 1,366 of 3,900 HCWs (35.0%) were vaccinated in the 2010/11 influenza season. Of the vaccinated HCWs, 1,323 (96.9%) completed the questionnaire in addition to 322 vaccinated medical students. Of the 1,645 vaccinees who completed the questionnaire, 712 had not been vaccinated against the influenza A(H1N1)2009 virus in the 2009/10 season. The main reason put forward was the objection to the AS03 adjuvants (239/712, 33.6%). Of the HCWs and students surveyed, 270 of 1,645 (16.4%) stated that the pandemic had influenced their attitude towards vaccination in general. Many German HCWs remained unconvinced of the safety of the pandemic (adjuvanted) influenza vaccine. For this reason, effective risk communication should focus on educating the public and HCWs about influenza vaccine safety and the benefits of vaccination.
甲型 H1N1 流感病毒的出现给全球卫生服务带来了重大挑战。然而，公众和医护人员（HCWs）的疫苗接种率仍然很低。我们进行了一项研究，以回顾 2009/10 年 HCWs 拒绝接种大流行性流感疫苗的原因，并描述 2010/11 年因甲型 H1N1 流感病毒出现而出现的流感季节的态度。在德国一家大学医院的流感疫苗接种运动期间，对 HCWs 和医学生进行了一项研究，使用匿名问卷对处于临床阶段的 HCWs 和医学生进行了调查。在 2010/11 年流感季节，有 3900 名 HCWs 中的 1366 名（35.0%）接种了疫苗。在接种疫苗的 HCWs 中，除了 322 名接种疫苗的医学生外，还有 1323 名（96.9%）填写了问卷。在完成问卷的 1645 名疫苗接种者中，有 712 人在 2009/10 年未接种甲型 H1N1 流感病毒疫苗。主要原因是反对使用 AS03 佐剂（239/712，33.6%）。在接受调查的 HCWs 和学生中，有 1645 名中的 270 名（16.4%）表示大流行总体上影响了他们对疫苗接种的态度。许多德国 HCWs 仍然不相信大流行性（佐剂）流感疫苗的安全性。因此，有效的风险沟通应侧重于向公众和 HCWs 宣传流感疫苗的安全性和接种疫苗的益处。
