Ahmed Zubair, Azad Najamul Sahar, Rauf Fouzia, Yaqoob Nausheen, Husain Akthar, Ahsan Aamir, Ahmed Rashida, Kayani Naila, Pervez Shahid, Hassan Sheema H
Department of Pathology and Microbiology, Aga Khan University Hospital, Karachi.
J Ayub Med Coll Abbottabad. 2007 Jul-Sep;19(3):56-63.
To determine in a large series of surgical biopsies, the frequency of various histologic types of primary solid malignant neoplasms in males and females in different age groups.
A retrospective study of 20,000 consecutive surgical biopsies reposted in the section of histopathology, AKU in 2004.
Malignant neoplasms are commonest in the fifth and sixth decades of life. The commonest malignant neoplasms in the first decade were Hodgkin's lymphoma and Wilm's tumor in males and females respectively. In the second decade, osteosarcoma in males and Ewing's sarcoma / PNET in females. In the third decade, colorectal adenocarcinoma in males and infiltrating. Ductal carcinoma of breast in females. In the fourth decade, squamous cell carcinoma of oral cavity in males and infiltrating ductal carcinoma of breast in females. In the fifth decade squamous cell carcinoma of oral cavity in males and infiltrating ductal carcinoma of breast in females. In sixth decade, squamous cell carcinoma of oral cavity in males and infiltrating ductal carcinoma of breast in females and in the seventh decade, prostatic adenocarcinoma in males and infiltrating ductal carcinoma of the breast in females. Above age of 70 years, the commonest malignant were again prostatic adenocarcinoma in males and infiltrating ductal carcinoma of breast in females.
Malignant neoplasms are commonest in the fourth, fifth and sixth decades of life.
在一系列大量手术活检中，确定不同年龄组男性和女性原发性实体恶性肿瘤各种组织学类型的发生率。
对2004年AKU组织病理学部分重新报告的20000例连续手术活检进行回顾性研究。
恶性肿瘤在生命的第五和第六个十年最为常见。第一个十年中最常见的恶性肿瘤，男性是霍奇金淋巴瘤，女性是肾母细胞瘤。第二个十年，男性是骨肉瘤，女性是尤因肉瘤/原始神经外胚层肿瘤。第三个十年，男性是结直肠腺癌，女性是浸润性乳腺癌。第四个十年，男性是口腔鳞状细胞癌，女性是浸润性乳腺癌。第五个十年，男性是口腔鳞状细胞癌，女性是浸润性乳腺癌。第六个十年，男性是口腔鳞状细胞癌，女性是浸润性乳腺癌，第七个十年，男性是前列腺腺癌，女性是浸润性乳腺癌。70岁以上，最常见的恶性肿瘤男性仍是前列腺腺癌，女性仍是浸润性乳腺癌。
恶性肿瘤在生命的第四、第五和第六个十年最为常见。
