Zamir Naima, Ahmed Soofia, Akhtar Jamshed
Department of Pediatric Surgery, National Institute of Child Health Karachi, Pakistan.
APSP J Case Rep. 2010 Jul;1(2):20. Epub 2010 Dec 1.
Bleeding per rectum is a common complaint in pediatric age group and mostly relates to benign conditions. Underlying colorectal carcinoma is a rare cause and carries a poor prognosis. We report two cases of mucinous adenocarcinoma of colon, one in a 9 years old male and other in a female of 12 years. The boy presented with rectal bleeding and increasing constipation of more than three years duration. He had mucinous adenocarcinoma (T3N0MX) of rectosigmoid region and underwent local complete resection of the tumor with colostomy. He also received postoperative chemotherapy and later underwent colostomy reversal. He is tumor free at two years follow up. The girl presented with signs of intestinal obstruction and at colonoscopy a stricture found in descending colon. The tumor was resected and biopsy reported as poorly differentiated mucinous adenocarcinoma with positive mesenteric nodes positive for tumor (T3N2MX). She is on chemotherapy.
直肠出血是儿科年龄段常见的主诉，大多与良性疾病有关。结直肠癌是其罕见病因，预后较差。我们报告两例结肠黏液腺癌，一例为9岁男性，另一例为12岁女性。该男孩出现直肠出血及持续三年以上的便秘加重症状。他患有直肠乙状结肠区域的黏液腺癌（T3N0MX），接受了肿瘤局部完整切除及结肠造口术。他还接受了术后化疗，之后进行了结肠造口还纳术。随访两年时无肿瘤复发。该女孩出现肠梗阻症状，结肠镜检查发现降结肠有狭窄。肿瘤切除后活检报告为低分化黏液腺癌，肠系膜淋巴结肿瘤阳性（T3N2MX）。她正在接受化疗。
