马达加斯加塔那那利佛附近伊科帕河谷一个高地村庄的恶性疟原虫疟疾传播指数。

Plasmodium falciparum malaria transmission indices in a highland village of the Ikopa River Valley near Antananarivo, Madagascar.

作者信息

Ralisoa O, Rasamindrakotroka A, Ravelojana B, Rafarasoa L, Randrianarisoa E, Rakotoson R, Bosman A, Coluzzi M

机构信息

Etablissement d'Enseignement Supérieur des Sciences, Université d'Antananarivo, Madagascar.

出版信息

Parassitologia. 1991 Dec;33(2-3):219-23.

PMID:1844515

Abstract

Data are reported from a malaria survey carried out in June 1991 in the small village of Ankadimbazinba, near Miantso, about 45 km North-West of Antananarivo (Madagascar). The objective was to evaluate the level of transmission of P. falciparum by entomological, parasitological and serological indices. All indices were found consistent with the description of a focus of hyperendemic transmission dependent on the presence of An. funestus at high density, corresponding to more than 50 females per house collected by hand catch. The positivity rate for the circumsporozoite protein (CS) of P. falciparum in blood-fed or gravid An. funestus was 2.0% (11/562) in the house resting sample. The parasite rate in the village population was 47.9% reaching 68.4% in the 0-14 age group and the gametocyte rate in the total sample was 25.0%. The seroprevalence of P. falciparum antisporozoite antibodies was 40.0% in children under 15 years old, 84.2% in the 15-29 age group and 90.9% in the over 29 age group.

摘要

数据来自1991年6月在安卡迪姆巴津巴小村庄进行的疟疾调查，该村庄位于米亚诺附近，距离塔那那利佛（马达加斯加）西北约45公里处。目的是通过昆虫学、寄生虫学和血清学指标评估恶性疟原虫的传播水平。所有指标均与一个高度流行传播疫源地的描述一致，该疫源地依赖于高密度的嗜人按蚊的存在，即通过人工捕捉，每户采集到50多只雌蚊。在室内栖息样本中，吸食血液或怀有身孕的嗜人按蚊中恶性疟原虫环子孢子蛋白（CS）的阳性率为2.0%（11/562）。村庄人口中的寄生虫感染率为47.9%，在0-14岁年龄组中达到68.4%，总样本中的配子体感染率为25.0%。15岁以下儿童中恶性疟原虫抗子孢子抗体的血清阳性率为40.0%，15-29岁年龄组中为84.2%，29岁以上年龄组中为90.9%。