Bosman A, Modiano D, Voglino M C, Pizzi L, Bartoloni P, Kandia Diallo I, De Giorgi F
Istituto di Parassitologia, Università La Sapienza, Roma, Italy.
Parassitologia. 1992 Dec;34(1-3):135-42.
A malaria survey based on household surveys and dispensary visits without notice was carried out during the rainy season of 1989 in three selected areas of central Futa Djalon (Republic of Guinea). Preliminary entomological evidence showed that Anopheles gambiae was the main vector in the area with a CS positive rate of 7.6% and a human blood index of 78% in August 1989. Indoor resting densities were highest in the rural village, lowest in Labé and intermediate in the town of Timbi Madina (median density per room of 18, 2 and 4.5, respectively). The household survey showed different parasite rates in the three areas: 78.2% of children had parasitaemia in Sombili, 45.8% in Timbi Madina and 16.7% in the urban sector of Labé. Prevalence and levels of P. falciparum antisporozoite antibodies were lowest in the urban area (seroprevalence of 51.9% and median titre of 2.4 arbitrary units), intermediate in the town (70.1% and 5.2) and highest in the rural village (78.9% and 5.8). Serological findings produced by dispensary visits were similar to those obtained with the household surveys except in the rural area, while parasitological data obtained with the two sampling methods were different both in rural and in urban areas. Routine malaria diagnosis made on a presumptive basis in the health services in the survey period was able to detect 30.1% of cases with parasitaemia and 53.2% of cases with hyperparasitaemia (sensitivity) and malaria was correctly not suspected in 82.8% of non parasitized people (specificity).
1989年雨季期间，在几内亚共和国富塔贾隆中部三个选定地区开展了一项基于家庭调查和不定期诊疗所访视的疟疾调查。初步昆虫学证据表明，冈比亚按蚊是该地区的主要病媒，1989年8月的环孢子虫阳性率为7.6%，人血指数为78%。室内栖息密度在农村村庄最高，在拉贝最低，在廷比马迪纳镇居中（每间房的中位数密度分别为18、2和4.5）。家庭调查显示三个地区的寄生虫感染率不同：松比利78.2%的儿童有寄生虫血症，廷比马迪纳为45.8%，拉贝市区为16.7%。恶性疟原虫抗子孢子抗体的流行率和水平在市区最低（血清流行率为51.9%，中位数滴度为2.4任意单位），在城镇居中（70.1%和5.2），在农村村庄最高（78.9%和5.8）。除农村地区外，诊疗所访视得出的血清学结果与家庭调查结果相似，而两种抽样方法在农村和城市地区获得的寄生虫学数据均有所不同。在调查期间，卫生服务机构基于推定进行的常规疟疾诊断能够检测出30.1%的寄生虫血症病例和53.2%的高寄生虫血症病例（敏感性），并且在82.8%的未感染寄生虫的人群中正确地未怀疑患有疟疾（特异性）。
