结肠溃疡性管状腺瘤中的骨化生：一例报告
Osseous metaplasia in an ulcerating tubular adenoma of the colon: a case report.
作者信息
White Victoria, Shaw Aidan G, Tierney Gillian M, Lund Jonathan N, Semeraro David
机构信息
School of Graduate Medicine and Health, University of Nottingham United Kingdom, Derby, UK.
出版信息
J Med Case Rep. 2008 Apr 29;2:130. doi: 10.1186/1752-1947-2-130.
Abstract
INTRODUCTION
Heterotopic bone is rarely found in the gastrointestinal tract. Here we report a rare case of metaplastic ossification within a benign ulcerating adenoma and review the literature concerning the aetiology.
CASE PRESENTATION
A 63-year-old woman, who presented with a history of melaena, was found at colonoscopy to have a pedunculated ulcerating polyp. Histological examination demonstrated multiple areas of osseous metaplasia within the polyp stroma.
CONCLUSION
Heterotopic ossification in colonic adenomas is a particularly rare phenomenon, with the majority of cases occurring within malignant lesions. The suggested mechanisms for its aetiology still remain unclear.
摘要
引言
胃肠道中很少发现异位骨。在此，我们报告一例罕见的良性溃疡性腺瘤内化生骨化病例，并回顾有关病因的文献。
病例介绍
一名63岁女性，有黑便病史，结肠镜检查发现有一个带蒂的溃疡性息肉。组织学检查显示息肉基质内有多个骨化生区域。
结论
结肠腺瘤中的异位骨化是一种特别罕见的现象，大多数病例发生在恶性病变中。其病因的推测机制仍不清楚。
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