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硬化治疗颈面部淋巴管畸形的重症监护经验。

Intensive care experience with sclerotherapy for cervicofacial lymphatic malformations.

作者信息

Ravindranathan Hari, Gillis Jonathan, Lord David J E

机构信息

Paediatric Intensive Care Unit, The Children's Hospital at Westmead, Sydney, Australia.

出版信息

Pediatr Crit Care Med. 2008 May;9(3):304-9. doi: 10.1097/PCC.0b013e31817287de.

Abstract

OBJECTIVE

To describe a cohort of patients needing intensive care support after sclerotherapy for cervicofacial lymphatic malformations.

DESIGN

Retrospective review of case records of patients undergoing sclerotherapy between January 2004 and November 2006.

SETTING

A tertiary, university-affiliated, pediatric teaching hospital.

PATIENTS

Five patients needing admission to a pediatric intensive care unit (PICU) following sclerotherapy with OK432.

INTERVENTIONS

None.

MEASUREMENTS AND MAIN RESULTS

Five patients needed a total of 13 PICU admissions. Ages ranged from 4 months to 19 months. All patients had extensive lesions that involved the airways, mediastinum, or floor of the mouth, documented by magnetic resonance imaging. Nine admissions involved elective intubation and ventilation following sclerotherapy due to the extent of lesions. There were four urgent admissions to the PICU with respiratory distress ranging from 3 to 18 days after sclerotherapy. The mean duration of admission was 7 days (total 93 days, range 2-22 days). Total ventilated hours were 1656 hrs with a range of 16.5-370 hrs per admission. Multiple procedures, such as drainage of cysts and further sclerotherapy procedures, were performed before extubation on the PICU.

CONCLUSIONS

Children with extensive disease and airway involvement need multiple PICU admissions. The potential for life-threatening respiratory embarrassment is unpredictable following sclerotherapy. Consideration should be given to performing further sclerotherapy while the patients are intubated in the PICU. The PICU provides a safe and secure environment for such procedures.

摘要

目的

描述一组在接受颈面部淋巴管瘤硬化治疗后需要重症监护支持的患者。

设计

对2004年1月至2006年11月期间接受硬化治疗的患者病例记录进行回顾性研究。

地点

一家三级大学附属儿科教学医院。

患者

5例接受OK432硬化治疗后需要入住儿科重症监护病房(PICU)的患者。

干预措施

无。

测量指标及主要结果

5例患者共需入住PICU 13次。年龄范围为4个月至19个月。所有患者均有广泛病变,累及气道、纵隔或口腔底部,磁共振成像证实。9次入住是由于病变范围在硬化治疗后进行选择性插管和通气。有4次在硬化治疗后3至18天因呼吸窘迫紧急入住PICU。平均住院时间为7天(共93天,范围2 - 22天)。总通气时长为1656小时,每次入住范围为16.5 - 370小时。在PICU拔管前进行了多种操作,如囊肿引流和进一步的硬化治疗操作。

结论

患有广泛疾病且累及气道的儿童需要多次入住PICU。硬化治疗后危及生命的呼吸窘迫可能性不可预测。应考虑在患者在PICU插管时进行进一步的硬化治疗。PICU为这类操作提供了一个安全可靠的环境。

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