Kholdebarin Ramin, Boetto Jonathan, Harnish Julie L, Urbach David R
Division of Clinical Decision Making and Health Care, Toronto General Hospital.
Surg Innov. 2008 Jun;15(2):114-9. doi: 10.1177/1553350608318144. Epub 2008 Apr 29.
Common bile duct injury is a serious but uncommon complication of laparoscopic cholecystectomy. A case-control epidemiologic study of patients who had undergone cholecystectomy in Ontario, Canada, between 1991 and 1997 was performed. Four patients who had undergone a laparoscopic cholecystectomy at the same hospital 2 months prior to a case were selected as controls. The risk of bile duct injury associated with various exposures was estimated by unconditional logistic regression. There were 28 cases and 88 controls. Emergency operation (adjusted odds ratio = 5.0; 95% confidence interval, 1.4-17.8) and failure to identify the cystic duct (adjusted odds ratio = 13.7; 95% confidence interval, 2.5-76.3) were statistically significant risk factors for operative bile duct injury. No other characteristics were independent risk factors for bile duct injury. Failure to identify the cystic duct and the emergency surgery are independent risk factors for bile duct injury.
胆总管损伤是腹腔镜胆囊切除术一种严重但并不常见的并发症。对1991年至1997年间在加拿大安大略省接受胆囊切除术的患者进行了一项病例对照流行病学研究。选取在病例发生前2个月于同一家医院接受腹腔镜胆囊切除术的4例患者作为对照。通过非条件逻辑回归估计与各种暴露相关的胆管损伤风险。共有28例病例和88例对照。急诊手术(调整后的优势比=5.0;95%置信区间,1.4 - 17.8)和未能识别胆囊管(调整后的优势比=13.7;95%置信区间,2.5 - 76.3)是手术胆管损伤的统计学显著危险因素。没有其他特征是胆管损伤的独立危险因素。未能识别胆囊管和急诊手术是胆管损伤的独立危险因素。