Yahalom Ran, Dobriyan Alex, Vered Marilena, Talmi Yoav P, Teicher Shlomo, Bedrin Lev
Department of Oral and Maxillofacial Surgery, The Chaim Sheba Medical Center, Tel Hashomer, Israel.
J Surg Oncol. 2008 Dec 15;98(8):572-8. doi: 10.1002/jso.21034.
A protocol was created for prospective margin status evaluation of patients with Oral SCC. Margins are evaluated intra- and post-operatively during three stages. Patients were divided into three groups: group 1 in which one margins were sampled randomly, group 2 with frozen sections taken from the surgical bed and 3 in which they were taken from the tumor specimen itself. Patients in group 3 showed the best correlation with final margin status and survival.
制定了一项用于口腔鳞状细胞癌患者切缘状态前瞻性评估的方案。在三个阶段对切缘进行术中及术后评估。患者被分为三组：第1组随机抽取一个切缘进行取样，第2组从手术床取冰冻切片，第3组从肿瘤标本本身取切片。第3组患者的切缘状态与最终切缘状态及生存率的相关性最佳。
