Grewal R P, Doppelt S H, Thompson M A, Katz D, Brady R O, Barton N W
Developmental and Metabolic Neurology Branch, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health, Bethesda, MD 20892.
Arch Neurol. 1991 Dec;48(12):1271-2. doi: 10.1001/archneur.1991.00530240075025.
We describe eight patients with type 1 Gaucher's disease who developed neurologic complications that were secondary to systemic features of the illness. Four patients experienced neurologic difficulties because of coagulopathy, and the other four patients had involvement of the nervous system secondary to skeletal disease. Early recognition of these complications in patients with type 1 Gaucher's disease may lead to improved neurologic outcome.
我们描述了8例1型戈谢病患者，他们出现了继发于该疾病全身特征的神经系统并发症。4例患者因凝血功能障碍出现神经功能障碍，另外4例患者的神经系统受累继发于骨骼疾病。早期识别1型戈谢病患者的这些并发症可能会改善神经功能预后。
