• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Diacylglycerol-protein kinase C signalling in skeletal muscle: a possible link to insulin resistance.

作者信息

Chen K S, Heydrick S, Kurowski T, Ruderman N B

机构信息

Evans Department of Medicine, Boston University School of Medicine, MA 02118.

出版信息

Trans Assoc Am Physicians. 1991;104:206-12.

PMID:1845146
Abstract
摘要

相似文献

1
Diacylglycerol-protein kinase C signalling in skeletal muscle: a possible link to insulin resistance.
Trans Assoc Am Physicians. 1991;104:206-12.
2
Enhanced stimulation of diacylglycerol and lipid synthesis by insulin in denervated muscle. Altered protein kinase C activity and possible link to insulin resistance.胰岛素对去神经支配肌肉中二酰甘油和脂质合成的增强刺激作用。蛋白激酶C活性改变及其与胰岛素抵抗的可能联系。
Diabetes. 1991 Dec;40(12):1707-11. doi: 10.2337/diab.40.12.1707.
3
Chronic effects of glucose on insulin signaling in A-10 vascular smooth muscle cells.葡萄糖对A-10血管平滑肌细胞胰岛素信号传导的慢性影响。
Arch Biochem Biophys. 1993 May;302(2):490-8. doi: 10.1006/abbi.1993.1244.
4
The role of diacylglycerol/protein kinase C signaling in insulin-stimulated glucose transport.
Trans Assoc Am Physicians. 1991;104:187-93.
5
Muscular diacylglycerol metabolism and insulin resistance.肌肉二酰甘油代谢与胰岛素抵抗
Physiol Behav. 2008 May 23;94(2):242-51. doi: 10.1016/j.physbeh.2007.12.002. Epub 2007 Dec 14.
6
Increased malonyl-CoA and diacylglycerol content and reduced AMPK activity accompany insulin resistance induced by glucose infusion in muscle and liver of rats.在大鼠的肌肉和肝脏中，葡萄糖输注诱导的胰岛素抵抗伴随着丙二酰辅酶A和二酰甘油含量的增加以及AMPK活性的降低。
Am J Physiol Endocrinol Metab. 2006 Mar;290(3):E471-9. doi: 10.1152/ajpendo.00316.2005. Epub 2005 Oct 18.
7
Pathophysiology of insulin resistance.胰岛素抵抗的病理生理学
Best Pract Res Clin Endocrinol Metab. 2006 Dec;20(4):665-79. doi: 10.1016/j.beem.2006.09.007.
8
Insulin-like effects of sodium orthovanadate on diacylglycerol-protein kinase C signaling in BC3H-1 myocytes.原钒酸钠对BC3H-1肌细胞中二酰甘油-蛋白激酶C信号传导的胰岛素样作用。
Arch Biochem Biophys. 1994 Jul;312(1):167-72. doi: 10.1006/abbi.1994.1295.
9
Pertussis toxin-sensitive and -insensitive mechanisms for diacylglycerol-protein kinase C signalling during insulin action in BC3H-1 myocytes.
Trans Assoc Am Physicians. 1990;103:195-201.
10
1,2-Diacylglycerol and ceramide levels in rat skeletal muscle and liver in vivo. Studies with insulin, exercise, muscle denervation, and vasopressin.
J Biol Chem. 1990 May 15;265(14):7933-8.

引用本文的文献

1
Quantification of muscle triglyceride synthesis rate requires an adjustment for total triglyceride content.定量肌肉甘油三酯合成率需要对总甘油三酯含量进行调整。
J Lipid Res. 2018 Oct;59(10):2018-2024. doi: 10.1194/jlr.D082321. Epub 2018 Aug 21.
2
Clinical effects of high-fat meals and weight gain due to high-fat feeding.高脂肪餐的临床效果及高脂喂养导致的体重增加。
Int J Obes Suppl. 2012 Dec;2(Suppl 2):S51-5. doi: 10.1038/ijosup.2012.23. Epub 2012 Dec 11.
3
Relationship between plasma free fatty acid, intramyocellular triglycerides and long-chain acylcarnitines in resting humans.
静息状态下人体血浆游离脂肪酸、肌内甘油三酯与长链酰基肉碱的关系。
J Physiol. 2009 Dec 15;587(Pt 24):5939-50. doi: 10.1113/jphysiol.2009.180695.
4
Effects of insulin and phorbol esters on MARCKS (myristoylated alanine-rich C-kinase substrate) phosphorylation (and other parameters of protein kinase C activation) in rat adipocytes, rat soleus muscle and BC3H-1 myocytes.胰岛素和佛波酯对大鼠脂肪细胞、大鼠比目鱼肌及BC3H - 1肌细胞中MARCKS（肉豆蔻酰化富含丙氨酸的C激酶底物）磷酸化（及蛋白激酶C激活的其他参数）的影响。
Biochem J. 1993 Oct 1;295 ( Pt 1)(Pt 1):155-64. doi: 10.1042/bj2950155.
5
Preferential activation of microsomal diacylglycerol/protein kinase C signaling during glucose treatment (De Novo phospholipid synthesis) of rat adipocytes.大鼠脂肪细胞葡萄糖处理（从头合成磷脂）过程中微粒体二酰甘油/蛋白激酶C信号通路的优先激活。
J Clin Invest. 1994 May;93(5):1894-9. doi: 10.1172/JCI117180.
6
Insulin increases mRNA levels of protein kinase C-alpha and -beta in rat adipocytes and protein kinase C-alpha, -beta and -theta in rat skeletal muscle.胰岛素可提高大鼠脂肪细胞中蛋白激酶C-α和-β的mRNA水平，以及大鼠骨骼肌中蛋白激酶C-α、-β和-θ的mRNA水平。
Biochem J. 1995 May 15;308 ( Pt 1)(Pt 1):181-7. doi: 10.1042/bj3080181.