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一项针对头颈癌患者的戒烟干预措施:试验设计、患者招募及特征

A smoking cessation intervention for head and neck cancer patients: trial design, patient accrual, and characteristics.

作者信息

Gritz E R, Carr C R, Rapkin D A, Chang C, Beumer J, Ward P H

机构信息

Division of Cancer Control, Jonsson Comprehensive Cancer Center, UCLA School of Medicine.

出版信息

Cancer Epidemiol Biomarkers Prev. 1991 Nov-Dec;1(1):67-73.

PMID:1845173
Abstract

This paper describes the aims, study design, and patient accrual and characteristics from an ongoing randomized controlled trial evaluating a surgeon- and dentist-delivered smoking cessation intervention for head and neck cancer patients. Subjects (n = 186) accrued into the trial are profiled in terms of demographics, medical and treatment descriptors, smoking history and behavior at enrollment, and related psychosocial variables (mood, adherence indicators, and alcohol consumption). These patients have long histories of tobacco use, moderate to high levels of nicotine dependence, and a lack of overt mood disturbance and are receptive to behavioral change.

摘要

本文描述了一项正在进行的随机对照试验的目的、研究设计、患者入组情况及特征,该试验评估了由外科医生和牙医为头颈癌患者提供的戒烟干预措施。纳入该试验的受试者(n = 186)根据人口统计学、医学和治疗描述、入组时的吸烟史及行为,以及相关的社会心理变量(情绪、依从性指标和饮酒情况)进行了分析。这些患者有长期吸烟史,尼古丁依赖程度为中度至高度,且没有明显的情绪障碍,愿意接受行为改变。

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