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在荧光镜引导下经皮肾镜取石术治疗下极肾结石的结果

Results of treatment of renal calculi with lower-pole fluoroscopically guided percutaneous nephrolithotomy.

作者信息

Nishizawa Koji, Yamada Hitoshi, Miyazaki Yu, Kobori Go, Higashi Yoshito

机构信息

Department of Urology, Ijinkai Takeda General Hospital, Kyoto, Japan.

出版信息

Int J Urol. 2008 May;15(5):399-402. doi: 10.1111/j.1442-2042.2008.01993.x.

Abstract

OBJECTIVE

To prospectively assess the clinical efficacy and safety of lower-pole fluoroscopically guided percutaneous nephrolithotomy (PNL).

METHODS

A total of 90 renal units in 87 patients underwent lower-pole fluoroscopically guided PNL for renal calculi. The average patient age was 56.0 years. Staghorn calculi were present in 41 renal units. There were 22 were upper pole, 54 middle pole, 76 lower pole, 70 pelvic and 18 ureteropelvic junction calculi. Patients without significant residual fragments greater than 3mm on postoperative day 2 were defined as primarily successful. Significant residual fragments were treated with shock wave lithotripsy (SWL) every other day from postoperative day 3.

RESULTS

Mean operative time was 129.5 min (SD, 49.0). Blood transfusion was required in four patients. Septic shock developed in three patients. Sixty-three percent of the patients (57 of 90 procedures) were primarily successful after PNL: 83.7% of non-staghorn patients (41 of 49 procedures) and 39.0% of staghorn patients (16 of 41 procedures). Of the 33 patients with significant residual fragments, 13 staghorn and six non-staghorn patients had residual fragments in their middle calyces. Of the preoperative variables, staghorn calculus and calculus in the middle calyx were significant predictors of significant residual fragments after PNL. After adjunctive SWL, the overall success rate was 94.5%.

CONCLUSIONS

Our study suggests that lower-pole fluoroscopically guided PNL is a safe and effective therapy for patients with staghorn or non-staghorn calculi. In patients with staghorn calculi or calculi in the middle calyx, adjunctive treatment is sometimes required to treat significant residual fragments.

摘要

目的

前瞻性评估在荧光透视引导下进行下极经皮肾镜取石术(PNL)的临床疗效和安全性。

方法

87例患者共90个肾单位接受了荧光透视引导下的下极PNL治疗肾结石。患者平均年龄为56.0岁。41个肾单位存在鹿角形结石。有22个上极结石、54个中极结石、76个下极结石、70个肾盂结石和18个输尿管肾盂连接处结石。术后第2天无大于3mm明显残留碎片的患者被定义为初次成功。术后第3天起,对有明显残留碎片的患者每隔一天进行冲击波碎石术(SWL)治疗。

结果

平均手术时间为129.5分钟(标准差49.0)。4例患者需要输血。3例患者发生感染性休克。63%的患者(90例手术中的57例)PNL术后初次成功:非鹿角形结石患者中83.7%(49例手术中的41例),鹿角形结石患者中39.0%(41例手术中的16例)。在33例有明显残留碎片的患者中,13例鹿角形结石患者和6例非鹿角形结石患者的中盏有残留碎片。在术前变量中,鹿角形结石和中盏结石是PNL术后有明显残留碎片的重要预测因素。辅助SWL治疗后,总体成功率为94.5%。

结论

我们的研究表明,荧光透视引导下的下极PNL对鹿角形或非鹿角形结石患者是一种安全有效的治疗方法。对于鹿角形结石或中盏结石患者,有时需要辅助治疗以处理明显的残留碎片。

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