Bayram Nihal Akar, Diker Erdem
Atatürk Eğitim ve Araştirma Hastanesi Kardiyoloji Kliniği, Ankara.
Turk Kardiyol Dern Ars. 2008 Jan;36(1):44-50.
Obstructive sleep apnea syndrome (OSAS) refers to recurring episodes of upper respiratory track obstruction and frequent decreases in arterial oxygen saturation due to repetitive occlusions of the posterior pharynx during sleep. Its prevalence in adult population is 4% in men and 2% in women. The most important causes of morbidity and mortality in affected patients are traffic accidents and cardiovascular complications including systemic arterial hypertension, coronary artery disease, congestive heart failure, and cardiac arrhythmias. The initial phases of apnea are associated with a transient increase in the parasympathetic activity resulting in bradyarrhythmias, followed by tachycardias due to increased sympathetic activity and arousal after the end of apnea episodes. The most frequent arrhythmia in OSAS is cyclic variation of heart rate. Most of the arrhythmias seen in OSAS are secondary to OSAS and disappear with OSAS treatment, without any electrophysiological conduction system abnormalities.
阻塞性睡眠呼吸暂停综合征（OSAS）是指睡眠期间后咽部反复阻塞导致上呼吸道反复阻塞发作以及动脉血氧饱和度频繁下降。其在成年人群中的患病率男性为4%，女性为2%。受影响患者发病和死亡的最重要原因是交通事故和心血管并发症，包括系统性动脉高血压、冠状动脉疾病、充血性心力衰竭和心律失常。呼吸暂停的初始阶段与副交感神经活动短暂增加有关，导致缓慢性心律失常，随后由于交感神经活动增加和呼吸暂停发作结束后的觉醒而出现快速性心律失常。OSAS中最常见的心律失常是心率的周期性变化。OSAS中出现的大多数心律失常继发于OSAS，随着OSAS的治疗而消失，且无任何电生理传导系统异常。
