Picazo M, Cuxart M, Sans R, Sardá C, Expósito E
Servicio de Nefrología, Hospital de Figueres.
Nefrologia. 2008;28(2):198-202.
Mesenteric ischaemia is an abdominal pathology with a high mortality rate. Among the population under dialysis treatment it presents some different traits such as non-occlusive mesenteric attacks in most of the cases. Its diagnosis is difficult and it is usually the result of an interdisciplinary collaboration. It is necessary to know better the symptoms of this illness among dialytic patients in order to improve its prognosis.
Eleven haemodialytic patients in our hospital (0.87% per patient-year) have diagnosed with mesenteric ischaemia confirmed by a laparothomy. We will list the main risk factors of this pathology, its symptoms, its evolution, some radiological and laboratory data more pointed out, the surgical findings anf its treatment.
Ten patients (91%) had suffer from cardiovascular pathologies, five of them (45%) had suffer an ischaemia cardiopathy. Seven patients (64%) had a spell of arterial hypotension during their haemodialysis session, which preceded mesenteric ischaemia. The reason for consulting a physician was abdominal pain, specially on the right hemiabdomen (64%). The analytical date most frequently observed was leucocytosis (54%). The usual radiological tests such as abdominal plain radiography and ecography didn't give any detailed formation. Ten out of eleven patients (91%) had necrosis on the intestinal wall. The ileum was the most affected intestinal section. Five of the patients presented only a limited damage of the ileum (45%). Two patients (18%) presented an extensive damage in the whole small intestine and part of the right colon. Intestinal resection was the most chosen way of treatment, which was practiced on eight patients (73%). Only three of them (27%) survived the mesenteric ischaemia and were sent to their homes. The key factor of their survival was that they were operated on in less than 8 hours from their arrival at emergency room.
Mesenteric ischaemia must be expected among patients under haemodialysis who suffer from abdominal pain, especially if they have had some arterial hypotensive spells during their previous dialytic session. It s a matter of urgent surgery where not only its diagnosis but also its early surgical treatment can lessen its high morbi-mortality risk.
肠系膜缺血是一种死亡率很高的腹部疾病。在接受透析治疗的人群中,它呈现出一些不同的特征,比如在大多数病例中表现为非闭塞性肠系膜发作。其诊断困难,通常需要多学科协作。为了改善透析患者中这种疾病的预后,有必要更深入了解其症状。
我院11例血液透析患者(每患者年发生率为0.87%)经剖腹手术确诊为肠系膜缺血。我们将列出这种疾病的主要危险因素、症状、病情发展、一些更具针对性的放射学和实验室数据、手术所见及其治疗方法。
10例患者(91%)患有心血管疾病,其中5例(45%)患有缺血性心脏病。7例患者(64%)在血液透析过程中出现动脉低血压发作,随后发生肠系膜缺血。就医原因是腹痛,尤其是右半腹疼痛(64%)。最常观察到的化验结果是白细胞增多(54%)。常规的放射学检查如腹部平片和超声检查未提供任何详细信息。11例患者中有10例(91%)肠壁出现坏死。回肠是受影响最严重的肠段。5例患者仅回肠有局限性损伤(45%)。2例患者(18%)整个小肠和部分右结肠出现广泛损伤。肠切除术是最常用的治疗方法,8例患者(73%)接受了该手术。其中只有3例(27%)在肠系膜缺血后存活并出院。他们存活的关键因素是在到达急诊室后8小时内接受了手术。
对于有腹痛的血液透析患者,尤其是在之前透析过程中曾出现动脉低血压发作的患者,必须考虑肠系膜缺血的可能。这是一个紧急手术问题,不仅其诊断,而且早期手术治疗都可以降低其高病死亡率风险。