Megakaryocyte cumulation in rabbit lungs after intraperitoneal administration of casein.

In the lung capillary vessels of rabbits, 24 hr after intraperitoneal administration of saturated casein solution, megakaryocyte cumulation (MK) was observed (22 MK/cm2 of section area in treated group and 2,5 MK/cm2 of section area in control group). Megakaryocytes were found most often in the form of an elongated nucleus without cytoplasm. The authors suppose, that MK liberation from the marrow into the venous vessels may be caused by casein degradation products.