Beggs Clive B, Kerr Kevin G, Noakes Catherine J, Hathway E Abigail, Sleigh P Andrew
Bradford Infection Group, School of Engineering, Design and Technology, University of Bradford, Bradford, UK.
Am J Infect Control. 2008 May;36(4):250-9. doi: 10.1016/j.ajic.2007.07.012.
Although the merits of ventilating operating theatres and isolation rooms are well known, the clinical benefits derived from ventilating hospital wards and patient rooms are unclear. This is because relatively little research work has been done in the ventilation of these areas compared with that done in operating theatres and isolation rooms. Consequently, there is a paucity of good quality data from which to make important decisions regarding hospital infrastructure. This review evaluates the role of general ward ventilation to assess whether or not it affects the transmission of infection.
A critical review was undertaken of guidelines in the United Kingdom and United States governing the design of ventilation systems for hospital wards and other multibed rooms. In addition, an analytical computational fluid dynamics (CFD) study was performed to evaluate the effectiveness of various ventilation strategies in removing airborne pathogens from ward spaces.
The CFD simulation showed the bioaerosol concentration in the study room to be substantially lower (2467 cfu/m(3)) when air was supplied and extracted through the ceiling compared with other simulated ventilations strategies, which achieved bioaerosol concentrations of 12487 and 10601 cfu/m(3), respectively.
There is a growing body of evidence that the aerial dispersion of some nosocomial pathogens can seed widespread environmental contamination, and that this may be contributing to the spread infection in hospital wards. Acinetobacter spp in particular appear to conform to this model, with numerous outbreaks attributed to aerial dissemination. This suggests that the clinical role of general ward ventilation may have been underestimated and that through improved ward ventilation, it may be possible to reduce environmental contamination and thus reduce nosocomial infection rates.
尽管手术室和隔离病房通风的益处广为人知,但医院病房和患者房间通风所带来的临床益处尚不清楚。这是因为与手术室和隔离病房相比,针对这些区域通风所开展的研究工作相对较少。因此,缺乏高质量的数据来为医院基础设施的重要决策提供依据。本综述评估普通病房通风的作用,以判断其是否会影响感染传播。
对英国和美国关于医院病房及其他多床位病房通风系统设计的指南进行了批判性综述。此外,进行了一项分析性计算流体动力学(CFD)研究,以评估各种通风策略在去除病房空气中病原体方面的有效性。
CFD模拟显示,与其他模拟通风策略相比,当通过天花板进行空气供应和抽取时,研究室内的生物气溶胶浓度显著更低(2467 cfu/m³),其他模拟通风策略的生物气溶胶浓度分别为12487 cfu/m³和10601 cfu/m³。
越来越多的证据表明,一些医院病原体的空气传播会导致广泛的环境污染,这可能促使医院病房内感染的传播。特别是不动杆菌属似乎符合这种模式,许多疫情暴发都归因于空气传播。这表明普通病房通风的临床作用可能被低估了,通过改善病房通风,有可能减少环境污染,从而降低医院感染率。