Savini Carolyn, James Christopher, Wilson Susan, Martin Heather, Szabo Susan, Scotto Vincenzo
HIV Program at Christiana Care Health System in Delaware, USA.
J Assoc Nurses AIDS Care. 2008 May-Jun;19(3):225-7. doi: 10.1016/j.jana.2007.11.005.
Of the recently approved antiretroviral protease inhibitors, atazanavir has become a popular medication for the treatment of HIV infection. The advantages of an atazanavir-based regimen include a favorable side effect profile, low impact on lipids, low pill burden, and daily dosing. These have made it a favorable choice for antiretroviral treatment. As more experience is gained with newer antiretroviral medications, additional side effects become apparent. Recent reports have highlighted occurrences of nephrolithiasis in patients using atazanavir-based regimens. The authors present a case of a patient who experienced nephrolithiasis while taking combination antiretroviral therapy that included atazanavir.
在最近获批的抗逆转录病毒蛋白酶抑制剂中，阿扎那韦已成为治疗HIV感染的常用药物。基于阿扎那韦的治疗方案的优势包括副作用较小、对脂质影响小、服药负担轻以及每日给药。这些使其成为抗逆转录病毒治疗的理想选择。随着对新型抗逆转录病毒药物有了更多经验，更多副作用变得明显。最近的报告强调了使用基于阿扎那韦方案的患者中肾结石的发生情况。作者报告了一例患者在接受包含阿扎那韦的抗逆转录病毒联合治疗时发生肾结石的病例。
