Tschubel K, Helpap B
Virchows Arch A Pathol Anat Histol. 1976 Sep 21;371(3):265-71. doi: 10.1007/BF00433073.
There were 700 tissue biopsies of the breast with and without carcinomas examined simultaneously by intraoperative histology and imprint cytology. In 20.2% of the cases with carcinoma the tumor cells showed peculiar intracytoplasmic inclusions, whereas in only 0.43% of the biopsies of the mamma without carcinoma such inclusions were to be found. Their morphologic variation and the histochemical pattern are discussed. It is pointed out that these intracytoplasmic inclusions may be a helpful histopathologic feature in the diagnosis of breast cancer.
对700例有癌和无癌的乳腺组织活检标本同时进行术中组织学和印片细胞学检查。在20.2%的癌病例中,肿瘤细胞显示出特殊的胞质内包涵体,而在仅0.43%的无癌乳腺活检标本中发现了此类包涵体。文中讨论了它们的形态学变异和组织化学模式。指出这些胞质内包涵体可能是乳腺癌诊断中一个有用的组织病理学特征。